- ￥2262
- LSM Bio
- 进口
- PAab08296
- 2025年07月17日
- ELISA,WB,IHC,IP
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
signal transducer and activator of transcription 2, 113kDa
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
signal transducer and activator of transcription 2, 113kDa
- 抗体英文名：
anti-STAT2 antibody,STAT2 antibody
- 抗体名：
anti-STAT2 抗体,STAT2 抗体
- 规格：
100μg
STAT2抗体| STAT2 antibody
货号 PAab08296
蛋白别名
蛋白介绍
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state (PubMed:9020188, PubMed:23391734). Acts as a regulator of mitochondrial fission by modulating the phosphorylation of DNM1L at 'Ser-616' and 'Ser-637' which activate and inactivate the GTPase activity of DNM1L respectively (PubMed:26122121).
产品描述
anti-STAT2 antibody is a Rabbit Polyclonal antibody againstSTAT2..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human breast cancer using PAab08296(STAT2 antibody) at dilution of 1:50
Western blot
HeLa cells were subjected to SDS PAGE followed by western blot with PAab08296(STAT2 antibody) at dilution of 1:500(本抗体仅供体外科研用途，不可用于临床诊断!) "">
""> ""> ""> ""> ""> "">风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验localization of phospho-STAT2 in the central nervous system (CNS) of mice. The procedures include single and dual/triple labeling immunostaining of phospho-STAT2 in the hippocampus of mice following entorhinal cortex lesion.
frank595 请问各位老师： JAK-STAT信号转导途径中的ISGF3可以使用Western Blot检测吗？如果可以如何检测？ 多谢！ yhwangcams Activated Stat2 forms a heterodimer with Stat1 and translocates to the nucleus. There, it associates with the DNA-binding
2R5C, PPP2R5D, PPP2R5E, PTEN, PRKCA, PRKCB1, PRKCZ, TCL1A, TCL1B. JAK and STAT Proteins: JAK1, JAK2, JAK3, STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, STAT6, TYK2. MAPK: MAPK1, MAPK3, MAPK6, MAPK7, MAPK8, MAPK9, MAPK10, MAPK11, MAPK12, MAPK13, MAPK
技术资料暂无技术资料 索取技术资料
