- ￥2262
- LSM Bio
- 进口
- PAab08351
- 2025年07月16日
- ELISA,WB,IHC,IP
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
serine/threonine kinase receptor associated protein
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
serine/threonine kinase receptor associated protein
- 抗体英文名：
anti-STRAP antibody,STRAP antibody
- 抗体名：
anti-STRAP 抗体,STRAP 抗体
- 规格：
100μg
STRAP抗体| STRAP antibody
货号 PAab08351
蛋白别名 MAWD antibody, UNRIP
蛋白介绍
The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. STRAP plays a role in the cellular distribution of the SMN complex. Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein.
产品描述
anti-STRAP antibody is a Rabbit Polyclonal antibody againstSTRAP..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human ovary using PAab08351(STRAP antibody) at dilution of 1:100
Western blot
mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab08351(STRAP antibody) at dilution of 1:2000(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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