SMAD3, also named as hMAD 3 or Mad3, is a 425 amino acid protein, which contains one MH1 domain and one MH2 domain. SMAD3 localizes in the nucleus and cytoplasm. SMAD3 plays an essential role in development and maintenance of self-tolerance and is a critical mediator of the TGFB signaling pathway. SMAD3 is involved in TGFB dependent regulation of steroidogenesis and in T-cell response to TGFB.
产品描述
anti-SMAD3 antibody is a Rabbit Polyclonal antibody againstSMAD3..
建议稀释比例
WB : 1:200-1:2000IHC : 1:20-1:200IF : 1:10-1:100
IHC
Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using PAab07994( SMAD3 Antibody) at dilution of 1:50
Western blot
Jurkat cells were subjected to SDS PAGE followed by western blot with PAab07994( SMAD3 Antibody) at dilution of 1:600(本抗体仅供体外科研用途,不可用于临床诊断!)