- ￥2262
- LSM Bio
- 进口
- PAab07884
- 2025年07月16日
- ELISA,WB,IHC
- E. coli - derived recombinant protein
- Human, Mouse ,Rat
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae)
- 抗体英文名：
anti-SIRT6 antibody,SIRT6 antibody
- 抗体名：
anti-SIRT6 抗体,SIRT6 抗体
- 规格：
100μg
SIRT6抗体| SIRT6 antibody
货号 PAab07884
蛋白别名 SIR2L6
蛋白介绍
NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF- kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. Required for genomic stability. Regulates the production of TNF protein. Has a role in the regulation of life span (By similarity). Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. On DNA damage, promotes DNA end resection via deacetylation of RBBP8. Has very weak deacetylase activity and can bind NAD(+) in the absence of acetylated substrate.
产品描述
anti-SIRT6 antibody is a Rabbit Polyclonal antibody againstSIRT6..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human brain using PAab07884(SIRT6 antibody) at dilution of 1:50
Western blot
human brain tissue were subjected to SDS PAGE followed by western blot with PAab07884(SIRT6 antibody) at dilution of 1:400(本抗体仅供体外科研用途，不可用于临床诊断!) "">
""> ""> ""> ""> ""> "">风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验
技术资料暂无技术资料 索取技术资料
