- ￥2262
- LSM Bio
- 进口
- PAab06363
- 2025年07月16日
- ELISA,WB,IHC
- E. coli - derived recombinant protein
- Human, Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
phosphoglycolate phosphatase
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9WVH4
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
phosphoglycolate phosphatase
- 抗体英文名：
anti-PGP antibody,PGP antibody
- 抗体名：
anti-PGP 抗体,PGP 抗体
- 规格：
100μl
PGP抗体| PGP antibody
货号 PAab06363
蛋白别名
蛋白介绍
Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3- phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear (PubMed:26755581). In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (By similarity).
产品描述
anti-PGP antibody is a Rabbit Polyclonal antibody againstPGP..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using PAab06363( PGP Antibody) at dilution of 1:50
Western blot
mouse heart tissue were subjected to SDS PAGE followed by western blot with PAab06363( PGP Antibody) at dilution of 1:1000(本抗体仅供体外科研用途，不可用于临床诊断!) <"">
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文献和实验Screening for P-Glycoprotein (Pgp) Substrates and Inhibitors
P-glycoprotein (P-gp), the product of the human ABCB1 gene and often called MDR1, is the best understood membrane protein known to be involved in the active transport of drugs across biological membranes. In addition to mediating or limiting
【摘要】目的 构建和表达抗CD3/抗Pgp微型双功能抗体，并测定该微型双功能抗体的生物学活性。方法 采用PCR和overlap PCR方法构建抗CD3/抗CD20微型双功能抗体，并用双脱氧终止法测定DNA序列；采用亲和层析法纯化该产物，并用Western blot和分子排阻层析鉴定纯化产物；采用免疫荧光法、放射免疫分析法和玫瑰花环试验鉴定纯化产物与靶细胞的结合活性。结果 DNA序列测定结果表明：抗CD3/抗Pgp微型双功能抗体已构建成功，表达可溶性产物的产量达2mg/l以上，纯化产物中二
Pharmacokinetic and Pharmacodynamic Implications of P-Glycoprotein Modulation
Modulation of P-glycoprotein (Pgp)-mediated transport has significant pharmacokinetic implications for Pgp substrates. Pharmacokinetic alterations may be at the systemic (blood concentrations), regional (organ or tissue concentrations
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