- ￥2262
- LSM Bio
- 进口
- PAab06182
- 2025年07月17日
- ELISA,WB,IF,IP
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
pre-B-cell leukemia homeobox 1
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9WVH4
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IF,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
pre-B-cell leukemia homeobox 1
- 抗体英文名：
anti-PBX1 antibody,PBX1 antibody
- 抗体名：
anti-PBX1 抗体,PBX1 抗体
- 规格：
100μl
PBX1抗体| PBX1 antibody
货号 PAab06182
蛋白别名 PRL
蛋白介绍
Binds the sequence 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the (1;19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation. Isoform PBX1b as part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Probably in complex with MEIS2, is involved in transcriptional regulation by KLF4. Acts as a transcriptional activator of NKX2-5 and a transcriptional repressor of CDKN2B. Together with NKX2-5, it is required for spleen development through a mechanism that involves CDKN2B repression (By similarity).
产品描述
anti-PBX1 antibody is a Rabbit Polyclonal antibody againstPBX1..
建议稀释比例
IHC
Western blot
(本抗体仅供体外科研用途，不可用于临床诊断!) <"">
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文献和实验(1;19)(q23;p13)染色体易位产生的E2A/PBX1融合mRNA；⑥t(10;14)(q24;q11)染色体易位；⑦检测B细胞肿瘤时t(14;18)染色体易位等血液系统恶性肿瘤多种基因重排，基因突变以及人类T.B淋巴细胞白血病等。
2K6, MAPK9, MATK, MDM2, MGAM, MHC2TA, MLL, MLL2, MLL3, MLL5, MLLT1, MLLT10, MLLT3, MLLT6, MLLT7, MME, MNDA, MPO, MVP, MYH11, NFATC1, NFATC3, NFIX, NF-ΚB2, NME3, NOTCH1, NPM1, NTRK1, NUP214, PAX5, PBX1, PBX2, PBX3, PDGFA, PHF11, PICALM, PIM1, POU2AF1, POU
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