- ￥2262
- LSM Bio
- 进口
- PAab05238
- 2025年07月15日
- ELISA,WB,IHC,IP
- E. coli - derived recombinant protein
- Human,Mouse ,Rat,Zebrafish
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat,Zebrafish
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P15248
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
- 抗体英文名：
anti-MMP2 antibody,MMP2 antibody
- 抗体名：
anti-MMP2 抗体,MMP2 抗体
- 规格：
100μg
MMP2抗体| MMP2 antibody
货号 PAab05238
蛋白别名 CLG4A
蛋白介绍
Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro- inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.
产品描述
anti-MMP2 antibody is a Rabbit Polyclonal antibody againstMMP2..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human gliomas tissue slide using PAab05238( MMP2 Antibody) at dilution of 1:200
Western blot
MCF7 cells were subjected to SDS PAGE followed by western blot with PAab05238(MMP2 antibody) at dilution of 1:500(本抗体仅供体外科研用途，不可用于临床诊断!) <"">
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文献和实验
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