- ￥2262
- LSM Bio
- 进口
- PAab03949
- 2025年07月08日
- ELISA,WB,IHC,IF,FC
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
heterogeneous nuclear ribonucleoprotein C (C1/C2)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P15248
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC,IF,FC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
heterogeneous nuclear ribonucleoprotein C (C1/C2)
- 抗体英文名：
anti-HNRNPC antibody,HNRNPC antibody
- 抗体名：
anti-HNRNPC 抗体,HNRNPC 抗体
- 规格：
100μg
HNRNPC抗体| HNRNPC antibody
货号 PAab03949
蛋白别名 HNRPC
蛋白介绍
Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles (PubMed:8264621). Specifically recognizes and binds N6- methyladenosine (m6A)-containing RNAs, a modification present at internal sites of mRNAs that affects mRNA splicing, processing and stability. M6A alters the local structure in mRNAs and long non- coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch' to facilitate binding of HNRNPC, leading to regulation of mRNA splicing (PubMed:25719671). Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre- mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'- UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules (PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621).
产品描述
anti-HNRNPC antibody is a Rabbit Polyclonal antibody againstHNRNPC..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human lymphoma using PAab03949(HNRNPC antibody) at dilution of 1:100
Western blot
HeLa cells were subjected to SDS PAGE followed by western blot with PAab03949(HNRNPC antibody) at dilution of 1:500(本抗体仅供体外科研用途，不可用于临床诊断!) <"">
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文献和实验
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