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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
serpin peptidase inhibitor, clade C (antithrombin), member 1
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9GZT9
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
Antithrombin III
- 抗体英文名:
anti-Antithrombin III antibody,Antithrombin III antibody
- 抗体名:
anti-Antithrombin III 抗体,Antithrombin III 抗体
- 规格:
100μg
Antithrombin III抗体| Antithrombin III antibody
货号 PAab00448
蛋白别名 Antithrombin antibody, Antithrombin III antibody, AT3 antibody, ATIII antibody, HEPARIN COFACTOR I antibody, Serpin C1 antibody, SERPINC1
蛋白介绍
SERPINC1, also named Antithrombin III or Antithrombin, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
产品描述
anti-Antithrombin III antibody is a Rabbit Polyclonal antibody againstAntithrombin III..
建议稀释比例
WB :1:200-1:1000;IF:1:50-1:500
IHC
Western blot
human blood tissue were subjected to SDS PAGE followed by western blot with PAab00448(SERPINC1 antibody) at dilution of 1:300(本抗体仅供体外科研用途,不可用于临床诊断!)
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文献和实验抗凝血酶III(Antithrombin,AT-III)的生理功能与临床应用
抗凝血酶III(Antithrombin,AT-III)概述 抗凝血酶III(AT-III),又称抗凝血酶(AT),是一种由肝脏合成的糖蛋白,属于丝氨酸蛋白酶抑制蛋白家族。除肝脏外,肺、肾、心、脾、肠、脑等器官也能合成AT。AT存在两种形式:α-AT(占90%)和β-AT(占10%)。 AT的功能机制 AT通过其反应中心环与靶蛋白酶的丝氨酸活性位点形成稳定复合物,从而不可逆地抑制凝血因子Ⅸa、Ⅹa、Ⅺa、Ⅻa以及Ⅶa与组织因子形成的复合体。这种抑制作用使其具有显著的抗血栓功能
in plasma were reported, leading to the classification of antithrombin in a range from I to IV. It was subsequently shown that these various antithrombin activities were the function of one molecule, antithrombin III, whose name was reduced to antithrombin
大鼠III型胶原(Collagen III)ELISA试剂盒 说明书
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 大鼠 III 型胶原 (Collagen III)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗大鼠 Collagen III 单抗包被于酶标板上,标准品和样品中的 Collagen III 与单抗结合,加入
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