重组人I-TAC/CXCL11报价

特别提示：包括重组人I-TAC/CXCL11在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人I-TAC/CXCL11
英文名称：Recombinant Human I-TAC/CXCL11
产品货号：GS4424
产品规格：5μg

分子量：Approximately 8.3kDa,a single non-glycosylated polypeptide chain containing 73 amino acids.
储存条件：冷冻（-20℃）

概述

CXCL11 also known as I-TAC is belonging to the CXC chemokine family and shares 36%and 37%amino acid sequence homology with IP-10 and MIG,respectively.It is highly expressed in peripheral blood leukocytes,pancreas and liver.Expression of CXCL11 is strongly induced by IFN-γ and IFN-β,and weakly induced by IFN-α.This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3,which with a higher affinity than do the other chemokines for this receptor,CXCL9 and CXCL10.Similar to CXCL10,CXCL11 has been shown to be a chemoattractant for IL-2-activated T-lymphocytes,but not for isolated T-cells,neutrophils or monocytes.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human IL-2 activated human T-lymphocytes is in a concentration range of 0.1-10ng/ml.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,100 mM NaCl.
内毒素	Less than 1 EU/μg of rHuI-TAC/CXCL11 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF

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