重组小鼠HB-EGF现货供应

特别提示：包括重组小鼠HB-EGF在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组小鼠HB-EGF
英文名称：Recombinant Murine Heparin-binding EGF-like Growth Factor
产品货号：GS4569
产品规格：10μg

分子量：Approximately 9.8kDa,a single non-glycosylated polypeptide chain containing 86 amino acids.
储存条件：冷冻（-20℃）

概述

Heparin-binding epidermal growth factor(HB-EGF)-like growth factor(EGF)is found in cerebral neurons.Its expression is increased after hypoxic or ischemic injury,which also stimulates neurogenesis.HB-EGF has been implicated as a participant in a variety of normal physiological processes such as blastocyst implantation and wound healing,and in pathological processes such as tumor growth,SMC hyperplasia and atherosclerosis.The protein is an 87 amino acid mitogenic and chemotactic glycoprotein containing an EGF-like domain with six conserved cysteine residues.Murine HB-EGF shares about 81%a.a.sequence identity with human HB-EGF.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 1ng/ml,corresponding to a specific activity of>1.0×106 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 10mMPB,500 mM NaCl,pH7.4.
内毒素	Less than 1 EU/μg of rMuHB-EGF as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	DLEGTDLNLF KVAFSSKPQG LATPSKERNG KKKKKGKGLG KKRDPCLRKY KDYCIHGECR YLQEFRTPSC KCLPGYHGHR CHGLTL

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