重组人Cathepsin S(组织蛋白酶S)

特别提示：包括重组人Cathepsin S(组织蛋白酶S)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人Cathepsin S(组织蛋白酶S)
英文名称：Recombinant Human Cathepsin S
产品货号：JN1730
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gln17-Ile331在C端含有His标签。

Cathepsin S质量控制：＞95%(还原性SDS-PAGE)

Cathepsin S制剂：液体

Cathepsin S保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于Cathepsin S：
Cathepsin S is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, cathepsin S is expressed in some epithelial cells. Compared with the abundant cathepsins B, L and H, cathepsin S shows a restricted tissue distribution, with highest levels in spleen, heart, and lung. In addition, evidences indicated that cathepsin S generates A beta from amyloidogenic fragments of beta APP in the endosomal/lysosomal compartment, and is implicated in the pathogenesis of Alzheimer’s disease (AD) and Down Syndrome (DS).


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