重组小鼠Lipocalin-2(NGAL)(C端含His标签

特别提示：包括重组小鼠Lipocalin-2(NGAL)(C端含His标签)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组小鼠Lipocalin-2(NGAL)(C端含His标签)
英文名称：Recombinant Mouse Neutrophil gelatinase-associated lipocalin
产品货号：JN1471
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gln21-Asn200在C端含有His标签。

Lipocalin-2/NGAL 质量控制：＞95%(还原性SDS-PAGE)

Lipocalin-2/NGAL 制剂：液体

Lipocalin-2/NGAL 保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于Lipocalin-2/NGAL ：
Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that enables it to be secreted and form complexes with matrix metalloproteinase-9 (MMP-9) through disulfide bonds. Similar to other lipocalin family members, Lipocalin-2 is involved in diverse cellular processes, including the transport of small hydrophobic molecules, protection of MMP-9 from proteolytic degradation, and cell signaling. Furthermore, Lipocalin-2 can tightly bind to bacterial siderophore through a cell surface receptor, possibly serving as a potent bacteriostatic agent by sequestering iron, regulating innate immunity and protecting kidney epithelial cells from ischemia–reperfusion injury. This protein is mainly expressed in neutrophils and in lower levels in the kidney, prostate, and epithelia of the respiratory and alimentary tracts. Recent evidence also suggests its role as a biomarker for renal injury and inflammation.

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