重组小鼠G-CSF北京厂家

特别提示：包括重组小鼠G-CSF在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组小鼠G-CSF
英文名称：Recombinant Murine Granulocyte Colony Stimulating Factor
产品货号：GS4690
产品规格：2μg

分子量：Approximately 18.9kDa,a single non-glycosylated polypeptide chain containing 178 amino acids.
储存条件：冷冻（-20℃）

概述

Granulocyte Colony Stimulating Factor(G-CSF)is a pleiotropic cytokine best known for its specific effects on the proliferation,differentiation,and activation of hematopoietic cells of the neutrophilic granulocyte lineage.It is produced mainly by monocytes and macrophages upon activation by endotoxin,TNFα and IFN-γ.Other cell types including fibroblasts,endothelial cells,astrocytes and bone marrow stromal cells can also secrete G-CSF after LPS,IL1 or TNF-α activation.In addition,various carcinoma cell lines and myeloblastic leukemia cells can express G-CSF constitutively.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞98%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine NFS-60 cells is less than 0.05ng/ml,corresponding to a specific activity of>2.0×107 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 10mMSodium Citrate,pH 4.0,150 mM NaCl,0.01%Tween-20.
内毒素	Less than 0.1 EU/μg of rMuG-CSF as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	VPLVTVSALP PSLPLPRSFL LKSLEQVRKI QASGSVLLEQ LCATYKLCHP EELVLLGHSL GIPKASLSGC SSQALQQTQC LSQLHSGLCL YQGLLQALSG ISPALAPTLD LLQLDVANFA TTIWQQMENL GVAPTVQPTQ SAMPAFTSAF QRRAGGVLAI SYLQGFLETA RLALHHLA

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