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Mouse G-CSF 重组小鼠粒细胞集落刺激因子(小鼠G-

CSF)
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  • ¥1855
  • 翌圣生物(Yeasen)已认证
  • 91107ES10
  • 上海
  • 2025年11月05日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保质期

      有效期1年

    • 保存条件

      -20℃至-80℃保存

    • 供应商

      翌圣生物科技(上海)股份有限公司

    • 库存

      大量

    • 英文名

      Recombinant Mouse Granulocyte Colony Stimulating Factor (Mouse G-CSF)

    • 规格

      10μg

    Product Information

     

    Product Name

    Cat#

    Size

    Price(¥

    Recombinant Mouse Granulocyte Colony Stimulating Factor (Mouse G-CSF)

    91107ES10

    10 μg

    1855.00

    91107ES60

    100 μg

    10215.00

    91107ES76

    500 μg

    26545.00

     

    Product Description

     

    Granulocyte colony stimulating factor (G-CSF) is a pleiotropic cytokine. It is produced mainly by monocytes and macrophages upon activation by endotoxin, TNF-alpha and IFN-gamma. Human G-CSF is 73% identical at the amino acid level to mouse G-CSF and the two proteins show species cross-reactivity. G-CSF receptor was expressed on cardiomyocytes and G-CSF activated the Jak/Stat pathway in cardiomyocytes. The G-CSF treatment did not affect initial infarct size at 3 d but improved cardiac function as early as 1 week after myocardial infarction. And the G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4.

     

    Product Properties

     产品细节图片1

    Synonyms

    G-CSF, CSF-3, MGI-1G, GM-CSF beta, MGC45931, Pluripoietin

    Accession

    P09920

    GeneID

    12985

    Source

    E.coli-derived mouse G-CSF protein, Val31-Ala208.

    Molecular Weight

    Approximately 18.9 kDa.

    AA Sequence

    VPLVTVSALP PSLPLPRSFL LKSLEQVRKI QASGSVLLEQ LCATYKLCHP EELVLLGHSL GIPKASLSGC SSQALQQTQC LSQLHSGLCL YQGLLQALSG ISPALAPTLD LLQLDVANFA TTIWQQMENL GVAPTVQPTQ SAMPAFTSAF QRRAGGVLAI SYLQGFLETA RLALHHLA

    Tag

    None

    Physical Appearance

    Sterile Filtered White lyophilized (freeze-dried) powder.

    Purity

    > 98% by SDS-PAGE and HPLC analyses.

    Biological Activity

    The ED50 as determined by a cell proliferation assay using mouse NFS-60 cells is less than 0.05 ng/mL, corresponding to a specific activity of > 2.0 × 107 IU/mg. Fully biologically active when compared to standard.

    Endotoxin

    < 0.1 EU per 1μg of the protein by the LAL method.

    Formulation

    Lyophilized from a 0.2 μm filtered concentrated solution in 10 mM Sodium Citrate, pH 4.0, 150 mM NaCl, 0.01% Tween-20.

    Reconstitution

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

     

    Shipping and Storage

     

    The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.

    Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

     

    Cautions

     

    Avoid repeated freeze-thaw cycles.

    For your safety and health, please wear lab coats and disposable gloves for operation.

    For research use only!

     

    HB220210

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    图标文献和实验
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