JN1832型重组人CD33(Siglec-3)品牌

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博主要从事生物试剂的生产和销*(代"售")，产品线涵盖JN1832型重组人CD33(Siglec-3)品牌在内的分子生物学试剂产品，还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。

名称：JN1832型重组人CD33(Siglec-3)品牌
规格：10μg|50μg|500μg|1mg
编号：JN1832
产地：国产|进口
英文名：Recombinant Human Sialic Acid Binding Ig-like Lectin 3
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Asp18-His259在C端含有Fc标签和His标签

CD33/Siglec-3质量控制：＞95%(还原性SDS-PAGE)

CD33/Siglec-3制剂：冻干品

CD33/Siglec-3保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CD33/Siglec-3复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CD33/Siglec-3：
CD33 is a type I Lectin belonging to the Ig superfamily. CD33 contains an N terminal Ig like V type domain, which mediates sialic acid binding, followed by one Ig like C2 type domain, a transmembrane region and a cytoplasmic tail containing two conserved immunoreceptor tyrosine based inhibition motifs (ITIMs). Eleven human Siglecs have been characterized. Siglecs 5 to 11 share a high degree of sequence similarity with CD33/Siglec3 both in their extracellular and intracellular regions. They are collectively referred to as CD33 related Siglecs. CD33 related Siglecs have differential expression pattern within the hematopoietic system. They are involved in the regulation of cellular activation within the immune system. Siglec 3 expression is restricted to cells of myelomonocytic lineage. Siglec3 recruits SHP1 and SHP2 to its ITIMs upon phosphorylation.

想要了解更多关于JN1832型重组人CD33(Siglec-3)品牌的价格、品牌、厂家、说明书、促销信息，请和我们联系。此外我公司还销*(代"售")下面的产品：
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EP101 PfuDNA Polymerase
BTN130986 即用型热启动PCR试剂盒 Instant Hotstart PCR Mix
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ARB11676 人趋化因子(frActAlkIne/CX3CL1)ELISA检测服务 Human fractalkine/cx3cl1 ELISA KIT
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JN1832型重组人CD33(Siglec-3)品牌关键词：重组人Siglec-3,重组CD33,JN1832,重组人CD33,重组人CD33蛋白


·重组人胰岛素样生长因子结合蛋白4(IGFBP-4)
编号：JN0526
英文名称：Recombinant Human Insulin-Like Growth Factor-Binding Protein 4
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Asp22-Glu258在C端含有His标签。

IGFBP-4质量控制：＞95%(还原性SDS-PAGE)

IGFBP-4制剂：冻干品

IGFBP-4保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

IGFBP-4复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于IGFBP-4：
Insulin-like growth factor binding protein 4 (IGFBP-4) is a 24 kDa protein that binds insulin-like growth factor 1 (IGF-1) and IGF-2 with high affinity and inhibits IGF action in vitro. All members of the IGFBP family can bind IGF-I and IGF-II with about equal affinity, but IGFBP-4 binds IGF2 more than IGF1. It contains IGFBP N-terminal domain and thyroglobulin type-1 domain. IGFBP-4 is induced by forskolin and N6, O2’dibutyryl sdenosine 3’, or 5’-cyclic monophosphate. The IGF-binding proteins can prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.


JN1832型重组人CD33(Siglec-3)品牌关键词：重组人Siglec-3,重组CD33,JN1832,重组人CD33,重组人CD33蛋白


·重组小鼠活化白细胞粘附分子(ALCAM)(CD166)
编号：JN1410
英文名称：Recombinant Mouse Activated Leukocyte Cell Adhesion Molecule
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Trp28-Lys527在C端带有Fc标签。

ALCAM /CD166质量控制：＞95%(还原性SDS-PAGE)

ALCAM /CD166制剂：冻干品

ALCAM /CD166保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

ALCAM /CD166复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于ALCAM /CD166：
Activated leukocyte cell adhesion molecule (ALCAM), also named as CD166 and MEMD, is a typeI transmembrane glycoprotein of immunoglobulin superfamily, which mediates homotypic and heterotypic interactions between cells. ALCAM interacts with high affinity with CD6 molecule but weaker homotypic (ALCAM–ALCAM) interactions have also been described. ALCAM–CD6 interactions play an important role in the maintenance of T cell activation, proliferation as well as in formation of immune synapse between antigen-presenting cell and lymphocytes. ALCAM is expressed on a wide variety of cells, particularly on activated lymphocytes, dendritic cells and monocytes, and on various epithelial cell types. It is also involved in multiple processes including embryogenesis, hematopoiesis, angiogenesis, and immune response. While expressed in a wide variety of tissues, ALCAM is usually restricted to subsets of cells in most adult tissues. Recently studies showed ALCAM has prognostic relevance in several human carcinomas, and it has been used as a biomarker for several tumor entities, including melanoma, gynecologic, urologic, and gastrointestinal cancers.

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