重组小鼠IL-22优惠促销

特别提示：包括重组小鼠IL-22在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组小鼠IL-22
英文名称：Recombinant Murine Interleukin-22
产品货号：GS4685
产品规格：2μg

分子量：Approximately 16.6kDa,a single non-glycosylated polypeptide chain containing 146 amino acids.
储存条件：冷冻（-20℃）

概述

IL-22 is belonging to IL-10 family of regulatory cytokines which includes IL-10,IL-19,IL-20,IL-22,IL-24 and IL-26.Members of this family share partial homology in their amino acid sequences,but they are dissimilar in their biological functions.Produced by T lymphocytes and dendritic cells,IL-10 contributes to the inflammatory response in vivo.IL-22 signals through CRF2-4 and IL-22.It along with IL-17 is rapidly produced by splenic LTi-like cells and can be also produced by Th17 cells and likely plays a role in the coordinated response of both adaptive and innate immune systems.Recombinant mouse interleukin-22 contains 147 amino acids and it has approximately 81%and 92%amino acid sequence identity with human and rat IL-22.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞96%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by inducing IL-10 secretion of human COLO 205 cells is less than 0.2ng/ml,corresponding to a specific activity of>5.0×106 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 1×PBS,pH 7.4.
内毒素	Less than 1 EU/μg of rMuIL-22 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	LPVNTRCKLE VSNFQQPYIV NRTFMLAKEA SLADNNTDVR LIGEKLFRGV SAKDQCYLMK QVLNFTLEDV LLPQSDRFQP YMQEVVPFLT KLSNQLSSCH ISGDDQNIQK NVRRLKETVK KLGESGEIKA IGELDLLFMS LRNACV

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