重组人HCC-1/CCL14北京厂家

特别提示：包括重组人HCC-1/CCL14在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人HCC-1/CCL14
英文名称：Recombinant Human Hemofiltrate CC Chemokine-1/CCL14
产品货号：GS4508
产品规格：2μg

分子量：Approximately 8.4kDa,a single non-glycosylated polypeptide chain containing 72 amino acids.
储存条件：冷冻（-20℃）

概述

Human CCL14 is belonging to the CC chemokine family.It has two isoforms,CCL14a(HCC-1)and CCL14b(HCC-3).The sequence of HCC-3 differs from HCC-1 as follow:27-27 R→ QTGGKPKVVKIQLKLVG.CCL14 was first isolated from the hemofiltrate of human patients with chronic renal failure.CCL14 promotes chemotaxis of T lymphocytes,monocytes and eosinophils,and inhibits infection of M-tropic human immunodeficiency virus type 1 and is a ligand for CCR1,CCR3 and CCR5.CCL14 is expressed constitutively in several normal tissues:spleen,liver,skeletal and heart muscle,gut,and bone marrow,present at high concentrations in plasma.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞96%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration of 5.0-20ng/ml.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,100 mM NaCl.
内毒素	Less than 1EU/μg of rHuHCC-1/CCL14 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	TESSSRGPYH PSECCFTYTT YKIPRQRIMD YYETNSQCSK PGIVFITKRG HSVCTNPSDK WVQDYIKDMK EN

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