重组大鼠IL-7北京现货

特别提示：包括重组大鼠IL-7在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组大鼠IL-7
英文名称：Recombinant Rat Interleukin-7
产品货号：GS4707
产品规格：2μg

分子量：Approximately 14.9kDa,a single non-glycosylated polypeptide chain containing 129 amino acids.
储存条件：冷冻（-20℃）

概述

Interleukin-7(IL-7)is encoded by the IL7 gene and secreted by stromal cells in the red marrow and thymus.It binds to the IL-7 receptor,a heterodimer consisting of IL-7 receptor alpha and IL-2 receptor gamma chain.IL-7 stimulates the differentiation of hematopoietic stem cells into lymphoid progenitor cells and also stimulates proliferation of B cells,T cells and NK cells.Furthermore,IL-7 as an immunotherapy agent has been examined in many human clinical trials for various malignancies and during HIV infection.Rat IL-7 contains 129 amino acid residues and has three disulfide bonds.In addition,it has approximately 57%and 88%amino acid sequence identity with human and murine IL-7.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞95%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine 2E8 cells is less than 2.0ng/ml,corresponding to a specific activity of>5.0×105 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 1 EU/μg of rRtIL-7 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	DCHIKDKDGK AFGSVLMISI NQLDKMTGTD SDCPNNEPNF FKKHLCDDTK EAAFLNRAAR KLRQFLKMNI SEEFNDHLLR VSDGTQTLVN CTSKEEKTIK EQKKNDPCFL KRLLREIKTC WNKILKGSI

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