重组猴S100B北京厂家

特别提示：包括重组猴S100B在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组猴S100B
英文名称：Recombinant Rhesus Macaque S100 Calcium Binding Protein B
产品货号：GS4557
产品规格：2μg

分子量：Approximately 10.6kDa,a single non-glycosylated polypeptide chain containing 91 amino acids
储存条件：冷冻（-20℃）

概述

S100B belongs to the S100 family,which containing 2 EF-hand calcium-binding motifs.In humans,S100B protein is encoded by the S100P gene located at 4q16,but genes that encode other numbers of s100 family proteins are almost located at 1q21 as a cluster.S100B is glial-specific and is expressed primarily by astrocytes.Not all astrocytes express S100B.It has been shown that S100B is only expressed by a subtype of mature astrocytes that ensheath blood vessels and by NG2-expressing cells.This protein may function in neurite extension,proliferation of melanoma cells,stimulation of Ca2+ fluxes,inhibition of PKC-mediated phosphorylation,astrocytosis and axonal proliferation,and inhibition of microtubule assembly.In the developing CNS it acts as a neurotrophic factor and neuronal survival protein.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Data Not Available.
成分	Lyophilized from a 0.2μmfiltered solution in PBS,pH 7.4.
内毒素	Less than 1 EU/μg of rRhS100B as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	SELEKAMVAL IDVFHQYSGR EGDKHKLKKS ELKELINNEL SHFLEEIKEQ EVVDKVMETL DSDGDGECDF QEFMAFVAMV TTACHEFFEH E

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