- ¥380 - 3800
- 百奥莱博
- L10046-QOX
- 北京
- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
57
- 英文名：
Abacavir
- CAS号：
136470-78-5
- 保质期：
长期
- 供应商：
北京百奥莱博科技有限公司
- 保存条件：
-20℃
- 规格：
1g|5g
特别提示：包括Abacavir在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
产品名称：Abacavir
英文名称：Abacavir
产品货号：L10046
产品规格：1g|5g
属性
| CAS号 | 136470-78-5 |
| 分子式 | C14H18N6O |
| 分子量 | 286.33 |
| 溶解性 | 25°C:DMSO<1mg/mL;Water 36 mg/mL;Ethanol<1mg/mL |
| 存贮条件 | 储存温度-20℃ |
描述
| 产品介绍 | Abacavir是强力的核苷类似物，为逆转录酶抑制剂。 |
| 生化机理 | Description:IC50 Value:0.26 microM for HIV-1[1]Abacavir,(-)-(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol,is a novel purine carbocyclic nucleoside analogue that has been approved by the FDA for the treatment of HIV(as Ziagen trade mark[abacavir sulfate])[2].in vitro:In erythrocytes,abacavir influx was rapid,nonsaturable(rate constant=200pmol/s/mM/microl cell water),and unaffected by inhibitors of nucleoside or nucleobase transport[2].in vivo:pharmacokinetic,distribution,and toxicological profiles of 1592U89 were distinct from and improved over those of CBV,probably because CBV itself was not appreciably formed from 1592U89 in cells or animals(<2%).The 5'-triphosphate of CBV was a potent,selective inhibitor of HIV-1 RT,with Ki values for DNA polymerases(alpha,beta,gamma,and epsilon which were 90-,2,900-,1,200-,and 1,900-fold greater,respectively,than for RT(Ki,21 nM).1592U89 was relatively nont |
| 别名 | 阿巴卡韦;(1S,4R)-4-[2-氨基-6-(环丙氨基)-9H-嘌呤-9-基]-2-环戊烯-1-甲chún;Ziagen;(1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol |
我公司销售的Abacavir(136470-78-5)，Ziagen，(1S,4R)-4-[2-氨基-6-(环丙氨基)-9H-嘌呤-9-基]-2-环戊烯-1-甲chún，(1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol，阿巴卡韦质量上佳，价格普惠，欢迎广大新老客户踊跃订购。
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文献和实验-stranded DNA template. A typical annealing temperature is 3-5°C lower than the calculated melting temperature of the primers. During the final stage, primer extension, the thermostable DNA polymerase carries out DNA synthesis
TP g/L 56.65±4.80 276 61.0-78
receptors for signaling. These and other new developments on the role of GRP78, GRP94 and GRP170 in cancer progression and therapy are discussed in this review. 葡萄糖调节蛋白似乎还包括GRP170 全文：fu2-5-7.pdf shaoliming Glucose
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