重组人IP-10/CXCL10北京现货

特别提示：包括重组人IP-10/CXCL10在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人IP-10/CXCL10
英文名称：Recombinant Human gamma-Interferon Inducible Protein 10/CXCL10
产品货号：GS4423
产品规格：5μg

分子量：Approximately 8.6kDa,a single non-glycosylated polypeptide chain containing 77 amino acids.
储存条件：冷冻（-20℃）

概述

CXCL10 also known as IP-10 is belonging to the CXC chemokine family.It is encoded by the CXCL10 gene.CXCL10 was originally identified in monocytes,endothelial cells and fibroblasts as a responsor to IFN-γ.This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3.CXCL10 has been shown to be a chemoattractant for activated T-lymphocytes and monocytes/macrophages.It also has other roles,such as promotion of T cell adhesion to endothelial cells,and inhibition of bone marrow colony formation and angiogenesis.The mouse homologue of human IP-10,Crg-2,has been cloned and shown to share approximately 67%amino acid sequence identity with human IP-10.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human peripheral blood T-lymphocytes is in a concentration range of 10-50ng/ml.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,50 mM NaCl.
内毒素	Less than 1 EU/μg of rHuIP-10/CXCL10 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	VPLSRTVRCT CIS*SNQPVN PRSLEKLEII PASQFCPRVE IIATMKKKGE KRCLNPESKA IKNLLKAVSK EMSKRSP

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