重组小鼠CT-1北京厂家

特别提示：包括重组小鼠CT-1在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组小鼠CT-1
英文名称：Recombinant Murine Cardiotrophin1
产品货号：GS4644
产品规格：2μg

分子量：Approximately 21.5kDa,a single non-glycosylated polypeptide chain containing 203 amino acids.
储存条件：冷冻（-20℃）

概述

Cardiotrophin-1(CT-1)is a member of the cytokine family which also includes IL-6,IL-11,leukemia inhibitory factor(LIF),oncostatin M(OSM),and ciliary neurotrophic factor(CNTF).CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart,skeletal muscle,ovary,colon,prostate and fetal lung.In addition,CT-1 which induces cardiac myocyte hypertrophy in vitro can bind to and activate the ILST/gp130 receptor.Murine CT-1 encodes a 203 amino acid(a.a.)residue protein that lacks a hydrophobic signal peptide.Human and murine CT-1 share 80%a.a.sequence identity and exhibit cross-species activity.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞95%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.5ng/ml,corresponding to a specific activity of>2.0×106 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 20mMTris,300 mM NaCl,pH 8.5.
内毒素	Less than 1 EU/μg of rMuCT-1 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	MSQREGSLED HQTDSSISFL PHLEAKIRQT HNLARLLTKY AEQLLEEYVQ QQGEPFGLPG FSPPRLPLAG LSGPAPSHAG LPVSERLRQD AAALSVLPAL LDAVRRRQAE LNPRAPRLLR SLEDAARQVR ALGAAVETVL AALGAAARGP GPEPVTVATL FTANSTAGIF SAKVLGFHVC GLYGEWVSRT EGDLGQLVPG GVA

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