重组人MCP-4/CCL13北京厂家

特别提示：包括重组人MCP-4/CCL13在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人MCP-4/CCL13
英文名称：Recombinant Human Monocyte Chemotactic Protein-4/CCL13
产品货号：GS4426
产品规格：5μg

分子量：Approximately 8.6kDa,a single non-glycosylated polypeptide chain containing 75 amino acids.
储存条件：冷冻（-20℃）

概述

Human CCL13 is belonging to the CC chemokine family and is encoded by the gene CCL13 in humans.CCL13(MCP-4)shares 56-61%sequence identity with MCP-1(CCL2)and MCP-3(CCL7)and is 60%identical to Eotaxin(CCL11).CCL13 was a potent chemoattractant for monocytes and eosinophils and stimulated histamine release from basophils.CCL13 can induce a calcium flux in HEK-293 cells transfected with the receptor CCR2B and CCR3.That shows the function receptors of CCL3 are CCR2B and CCR3.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞96%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration of 10-100ng/ml.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,130 mM NaCl.
内毒素	Less than 1 EU/μg of rHuMCP-4/CCL13 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	QPDALNVPST CCFTFSSKKI SLQRLKSYVI TTSRCPQKAV IFRTKLGKEI CADPKEKWVQ NYMKHLGRKA HTLKT

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