重组人Endostatin北京厂家

特别提示：包括重组人Endostatin在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人Endostatin
英文名称：Recombinant Human Endostatin
产品货号：GS4663
产品规格：20μg

分子量：Approximately 19.8kDa,a single non-glycosylated polypeptide chain containing 177 amino acids(C-terminal fragment of collagen XVIII).
储存条件：冷冻（-20℃）

概述

Endostatin has been identified as a C-terminal fragment of Collagen type 18,a recently identified member of a family of collagen-like proteins referred to as multiplexin family.Endostatin specifically inhibits proliferation of endothelial cells although it does not affect the proliferation of EOMA cells.Endostatin also potently inhibits angiogenesis and tumor growth.Endostatin has an important role in endothelial cell adhesion and cytoskeletal organization.Endostatin can be found in vessel walls(elastic fibers)and basement membranes.Recombinant Endosatin expressed in yeast causes G1 arrest of endothelial cells,and endostatin treatment results in apoptosis of HUVE and HMVE cells.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞96%by SDS-PAGE and HPLC analyses.
来源	Pichia Pastoris
生物活性	Fully biologically active when compared to standard.The ED50 as determined by inhibiting the FGF basic-dependent proliferation of HUVEC migration is less than 2.0μg/mL in the presence of Anti-Human Endostatin Polyclonal Antibody.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 1 EU/μg of rHuEndostatin as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	NYEKPALHLA ALNMPFSGDI RADFQCFKQA RAAGLLSTYR AFLSSHLQDL STIVRKAERY SLPIVNLKGQ VLFNNWDSIF SGHGGQFNMH IPIYSFDGRD IMTDPSWPQK VIWHGSSPHG VRLVDNYCEA WRTADTAVTG LASPLSTGKI LDQKAYSCAN RLIVLCIENS FMTDARK

我公司销售的重组人Endostatin北京厂家，rEndostatin，重组Endostatin，Recombinant Human Endostatin，rhEndostatin，Endostatin, Human，重组人Endostatin质量上佳，价格普惠，欢迎广大新老客户踊跃订购。