- ￥1380 - 3580
- Elabscience
- E-AB-60391
- 武汉
- 2026年09月23日
- IF
- Rabbit
- Human;Mouse;Rat
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- 文献和实验
- 技术资料
- 抗体名：
PD-L1 Polyclonal Antibody_货号:E-AB-60391_多克隆抗体
- 抗体英文名：
PD-L1 Polyclonal Antibody
- 靶点：
PD-L1
- 浓度：
5 μL/Test
- 应用范围：
IF
- 宿主：
Rabbit
- 适应物种：
Human;Mouse;Rat
- 保质期：
12个月
- 级别：
科研
- 库存：
99
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 标记物：
Unconjugated
- 克隆性：
Polyclonal
- 保存条件：
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 形态：
液体
- 亚型：
IgG
- 规格：
200μL/120μL/60μL
| 规格： | 200μL | 产品价格： | ￥3580.0 |
|---|---|---|---|
| 规格： | 120μL | 产品价格： | ￥2220.0 |
| 规格： | 60μL | 产品价格： | ￥1380.0 |
货号：E-AB-60391
| Verified Samples |
Verified Samples in IF: RAW264.7
|
| Dilution |
IF 1:50-1:200
|
| Clonality |
Polyclonal
|
| Isotype |
IgG
|
| Immunogen |
Recombinant fusion protein of human PD-L1 (NP_054862.1).
|
| Abbre |
PD-L1
|
| Synonyms |
B7-H;B7H1;PDL1;PD-L1;PDCD1L1;PDCD1LG1;CD274抗体
|
| Swissprot |
Q9NZQ7
|
| Cellular Localization |
Cell membrane and Endomembrane system.
|
| Concentration |
1mg/mL
|
| Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
| Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
|
| Purification Method |
Affinity purification
|
| Research Areas |
Cancer; Immunology
|
| Conjugation |
Unconjugated
|
| Background |
This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.
|
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文献和实验A Trojan Horse Delivery Vehicle Carrying siRNA Nanotherapeutics with Multiple Tumor Microenvironment Responsiveness Elicits Robust Antitumor Immune Responses In Situ via a “Self-Synergistic” Approach
IF:10
Journal:Advanced Healthcare Materials
DOI:10.1002/adhm.202301401
Construction of Polyclonal Antibody Libraries Using Phage Display
Polyclonal antibody libraries (PCALs) are standardized mixtures of antibodies (Abs) specific for an antigen (Ag) or multi-Ag target (a poly-Ag). As the immunoglobulin (Ig) genes are cloned, the mixtures can be perpetuated, amplified
因此，综合来说，EarthOx的GST标签抗体 （货号#E022040）是一款同时具有高特异性、高灵敏度、多应用类型以及性价比的GST标签抗体。同时，我们也提供其他品牌的GST标签抗体，如Proteintech的GST多克隆抗体 ――GST PolyClonal Antibody（货号#10000-0-AP）以及Abcam、Santa等多种GST标签抗体产品。更多GST标签抗体以及其他如His、HA、Myc、GFP、Flag等其他标签抗体，请电话垂询。美国EarthOx品牌是一家提供高性价比免疫学和细胞
后，目标蛋白不会存在于样品中，因此成为绝佳的阴性对照。与对照组一起进行对比试验，抗体是否特异则一目了然。以近期热门的 PD-L1 抗体为例：上图显示了对野生型 L2987 细胞（左图）和 PD-L1 基因敲除 （KO） L2987 细胞系（右图）使用抗 PD-L1 [28-8] RabMAb® 抗体（ab205921）的染色情况。利用 TALEN 编辑 L2987 结肠直肠癌细胞系中的 PD-L1 基因，靶向人 PD-L1 的第 4 外显子。通过深度测序可确认 KO 已完成。记得哦，这才是杂志
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