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- 文献和实验
- 技术资料
- 抗体名:
NOX4 Polyclonal Antibody_货号:E-AB-70215_多克隆抗体
- 抗体英文名:
NOX4 Polyclonal Antibody
- 靶点:
NOX4
- 浓度:
5 μL/Test
- 应用范围:
WB;IHC
- 宿主:
Rabbit
- 适应物种:
Human;Mouse;Rat
- 保质期:
12个月
- 级别:
科研
- 库存:
99
- 供应商:
武汉伊莱瑞特生物科技股份有限公司
- 标记物:
Unconjugated
- 克隆性:
Polyclonal
- 保存条件:
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 形态:
液体
- 亚型:
IgG
- 规格:
200μL/120μL/60μL
| 规格: | 200μL | 产品价格: | ¥3300.0 |
|---|---|---|---|
| 规格: | 120μL | 产品价格: | ¥2220.0 |
| 规格: | 60μL | 产品价格: | ¥1380.0 |
货号:E-AB-70215
| Verified Samples |
Verified Samples in WB:Rat skeletal muscle,Rat lung,Rat kidney
Verified Samples in IHC:Human kidney,Mouse kidney |
| Dilution |
WB 1:1000-1:2000, IHC 1:400-1:1000
|
| Clonality |
Polyclonal
|
| Isotype |
IgG
|
| Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse NOX4
|
| Abbre |
NOX4
|
| Synonyms |
Kidney oxidase 1;Kidney oxidase-1;Kidney superoxide producing NADPH oxidase;Kidney superoxide-producing NADPH oxidase;KOX 1;KOX;Kox-1;KOX1;NADPH;NADPH oxidase 4;Nox4;NOX4;Renal NAD(P)H oxidase;Renal NAD(P)H-oxidase;RENOX抗体
|
| Swissprot |
Q9NPH5,Q9JHI8,Q924V1
|
| Calculated MW |
70kDa
|
| Observed MW |
70kDa
|
| Cellular Localization |
Endoplasmic reticulum membrane. Cell membrane. Cell junction>focal adhesion. Nucleus. May localize to plasma membrane and focal adhesions. According to PubMed:15927447, may also localize to the nucleus.
|
| Concentration |
0.9 mg/mL
|
| Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
| Buffer |
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
|
| Purification Method |
Affinity purification
|
| Research Areas |
Cancer; Cell Biology; Cardiovascular; Metabolism; Signal Transduction
|
| Conjugation |
Unconjugated
|
| Background |
This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
|
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