手机验证
ABI1 Polyclonal Antibody_货号:E-AB-15453_多克隆抗体
ABI1 Polyclonal Antibody
WB;IHC;ELISA
Rabbit
Human;Mouse;Rat
12个月
E-AB-15453
科研级别
999
武汉伊莱瑞特生物科技股份有限公司
Unconjugated
Polyclonal
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
液体
IgG
200μL/120μL/60μL/20μL
规格: | 200μL | 产品价格: | ¥2365.0 |
---|---|---|---|
规格: | 120μL | 产品价格: | ¥1640.0 |
规格: | 60μL | 产品价格: | ¥1010.0 |
规格: | 20μL | 产品价格: | ¥420.0 |
Verified Samples |
Verified Samples in WB:Human brain
Verified Samples in IHC:Human cervical cancer,Human gastric cancer |
Dilution |
WB 1:500-1:2000, IHC 1:50-1:200
|
Clonality |
Polyclonal
|
Isotype |
IgG
|
Immunogen |
Synthetic peptide of human ABI1
|
Abbre |
ABI1
|
Synonyms |
Abelson interactor 1;Abi-1;Abi1;ABI1;Abl binding protein 4;Abl interactor 1;Abl interactor protein 1;Abl-binding protein 4;AblBP4;e3B1;Eps8 binding protein;Eps8 SH3 domain binding protein;Eps8 SH3 domain-binding protein;Eps8-binding protein;Hssh3bp1;Interactor protein AblBP4;NAP1;Nap1 binding protein;Nap1-binding protein;Nap1BP;Spectrin SH3 domain binding protein 1;Spectrin SH3 domain-binding protein 1;SSH3BP抗体
|
Swissprot |
Q8IZP0
|
Calculated MW |
55kDa
|
Cellular Localization |
Cytoplasm. Nucleus. Cell projection>lamellipodium. Cell projection>filopodium. Cell projection>growth cone. Cell junction>synapse>synaptosome. Cytoplasm>cytoskeleton. Localized to protruding lamellipodia and filopodia tips. Also localized to neuronal growth cones and synaptosomes.
|
Concentration |
0.6 mg/mL
|
Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
Buffer |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
|
Purification Method |
Affinity purification
|
Research Areas |
Cell Biology; Signal Transduction
|
Conjugation |
Unconjugated
|
Background |
This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14
|
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
自2012年第一篇引用文献问世,至2023年8月,Elabscience已协助各地科研工作者发表超13,000篇SCI文献,包括行业顶/级期刊Nature Medicine, Nature, Cell, Signal Transduction and Targeted Therapy, Circulation, Molecular Cancer, Immunity, Advanced Materials等,总影响因子(IF)59472.59,其中IF≥30的文献超30篇,最高影响因子为66.849,发文单位包含北京大学、中国科学技术大学、浙江大学、斯坦福大学、耶鲁大学、柏林夏里特大学等国内外各大高校。
每年引用文献数量持续增长,保持逐年30%+高增长率,可以预见,Elabscience产品将帮助更多科研工作者发表高质量SCI论文。
文献详情查看>>>>