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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
Mouse IgG2b, κ
- 形态:
液体
- 保存条件:
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
- 克隆性:
Monoclonal
- 标记物:
PE/Cyanine 5
- 适应物种:
Human
- 保质期:
12个月
- 目录编号:
E-AB-F1212H
- 级别:
科研
- 库存:
999
- 供应商:
武汉伊莱瑞特生物科技股份有限公司
- 宿主:
Mouse
- 应用范围:
FCM
- 抗体英文名:
PE/Cyanine7 Anti-Human CD20 Antibody[2H7]_货号:E-AB-F1212H
- 抗体名:
PE/Cyanine7 Anti-Human CD20 Antibody流式抗体[2H7]_货号:E-AB-F1212H
- 规格:
100Tests/20Tests/100Tests×2
| 规格: | 100Tests | 产品价格: | ¥3168.0 |
|---|---|---|---|
| 规格: | 20Tests | 产品价格: | ¥1224.0 |
| 规格: | 100Tests×2 | 产品价格: | ¥4752.0 |

PE/Cyanine7 Anti-Human CD20 抗体流式抗体[2H7]产品名称:PE/Cyanine7 Anti-Human CD20 Antibody[2H7], 货号:E-AB-F1212H
| 产品描述: | CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82. |
| Alternate Names | Bp35;Leukocyte surface antigen Leu-16;MS4A1;B-lymphocyte surface antigen B1; |
| Swissprot | P11836 |
| Gene ID | 931 |
| Clone No | 2H7 |
| Host | Mouse |
| Reactivity | Human |
| Application | FCM |
| 同种型 | Mouse IgG2b, κ |
| 同种型 Control | PE/Cyanine7 Mouse IgG2b, κ 同种型 Control[MPC-11] |
| Conjugation | PE/Cyanine7 |
| Conjugation Information | PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter). |
| Spectrum | |
| 储存方法 缓冲 | Phosphate 缓冲ed solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| 储存方法 | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration date | 12个月 |
| Shipping | 冰袋 |

PE/Cyanine7 Anti-Human CD20 抗体流式抗体[2H7]labscience®拥有先进的单抗,多抗和流式抗体开发技术平台,提供8500+高品质 抗体, 适用于胞内和胞外蛋白的鉴定、定量和定位研究。抗体已在多种应用中得到验证,包含 流式细胞术(Flow Cytometry)、 免疫印迹(WB)、 免疫组化(IHC/ICC)、 免疫(共)沉淀(IP/Co-IP)、 免疫荧光(IF) 等实验。抗体产品涉及多种生命科学研究领域,包括肿瘤、免疫、心血管、细胞生物学、神经科学、表观遗传学等。Elabscience®始终致力于提高抗体的质量和种类,以保障并加快您的研究进程
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.PE/Cyanine7 Anti-Human CD20 抗体流式抗体[2H7]产品更多产品信息查看欢迎咨询我们和搜索武汉伊莱瑞特Elabscience官网查看。
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文献和实验membrane, creating a structure similar to an ion channel Delivers early signal in B cell activation, allowing resting B cells to respond to later antigens Rituximab is a chimeric murine-human anti-CD20 antibody used for treatment of B cell
69、CD38 等活化指标,及 IFN-γ、IL-4、IL17A 等细胞因子,则需要设置同型对照,实现阴阳性细胞群的良好区分。 CD4 CD25 (2)在某些特殊情况下,如单核细胞被 PE/Cyanine 7、APC/Cyanine 7 等串联染料标记的抗体染色时,使用同型对照抗体是十分有必要的。单核细胞一般倾向于与 Cyanine7 等染料非特异性结合,使用同型对照抗体有助于获得理想结果。 (3)不清楚抗原表达情况的时候,一定要使用同型对照来界定阴性细胞群。 (4)胞内染色时
因为抗体的结合而减少;在人体血清中无游离的CD20存在;最重要的是B淋巴细胞瘤上的CD20少有内吞和脱落的发生[ 2-5 ] 。1997年,以CD20为靶点的嵌合抗CD20单克隆抗体Rituxan已获准应用于B细胞淋巴瘤的治疗[ 6 ]。HI47(IgG3)是我所于1990年研制成功的国内第一个抗CD20鼠源性单克窿抗体,第四届国际人类白细胞分化抗原会议将HI47命名为CD20+X[ 7 ] 。我们利用噬菌体显示技术从HI47杂交瘤细胞中克隆到抗CD20抗体HI47可变区基因,将该基因构建成为嵌合的抗
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