E-Cadherin Monoclonal Antibody

Verified Samples in IHC:Mouse liver,Rat colon,Rat pancreas

IHC 1:200-1:800

Monoclonal

IgG

Recombinant protein corresponding to MouseE-cadherin

E-Cadherin

Arc 1;CADH1;Cadherin 1;cadherin 1 type 1 E-cadherin;Cadherin1;CAM 120/80;CD 324;CD324;CD324 antigen;cdh1;CDHE;E-Cad/CTF3;E-cadherin;ECAD;Epithelial cadherin;epithelial calcium dependant adhesion protein;LCAM;Liver cell adhesion molecule;UVO;Uvomorulin抗体

P09803,Q9R0T4

1.6 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Affinity purification

Cancer; Developmental Biology; Signal Transduction

EC125D

Unconjugated

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.