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- 详细信息
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- 规格:
1 mg/5 mg
| 规格: | 1 mg | 产品价格: | ¥2500.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥6000.0 |
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Saikogenin A
CAS No. : 5092-09-1
MCE 国际站:Saikogenin A
产品活性:Saikogenin A 可从中药柴胡中提取,是一种二肽基肽酶 IV (DPP-IV) 抑制剂。
研究领域:Metabolic Enzyme/Protease
作用靶点:Dipeptidyl Peptidase
In Vitro: Saikogenin A has certain inhibitory effect on the enzyme DPP-IV. At a concentration of 20 μg/mL DPP-IV inhibition is 47.6%. DPP-IV is a non-classical serine aminopeptidase from its amino terminus of polypeptides and proteins (N-terminus) removing Xaa-Pro dipeptide.
In Vivo: Saikogenin A, an anti-inflammatory drug, is present in the crude extract of a Chinese herbal plant called Tsai-Fu. Saikogenin A is less effective in adrenalectomized rats than in normal rats in reducing the carrageenin-induced edema. The anti-inflammatory action of Saikogenin A are due to an increase in corticosterone caused by the release of arenocorticotropic hormone (ACTH) and a direct effect on the process of inflammation.
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