相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
41059-79-4
- 规格:
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥1434.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥304.0 |
| 规格: | 5 mg | 产品价格: | ¥821.0 |
| 规格: | 10 mg | 产品价格: | ¥1463.0 |
| 规格: | 25 mg | 产品价格: | ¥2475.0 |
| 规格: | 50 mg | 产品价格: | ¥3713.0 |
| 规格: | 100 mg | 产品价格: | ¥5569.0 |
MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务。
Timosaponin AIII
CAS No. : 41059-79-4
MCE 国际站:Timosaponin AIII
产品活性:Timosaponin AIII 能够抑制乙酰胆碱酯酶 (AChE) 的活性,其 IC50 值为 35.4 μM。
研究领域:Neuronal Signaling
作用靶点:Cholinesterase (ChE)
In Vitro: Timosaponin AIII could inhibit acetylcholinesterase (AChE) activity, with an IC50 of 35.4 μM. Timosaponin AIII is identified as a major selective cytotoxic activity in BN108, and its selective cytotoxic activity involves inhibition of mTOR, induction of ER stress and protective autophagy.
In Vivo: Of the tested steroidal saponins, Timosaponin AIII (TA3) most potently improves memory deficits. Timosaponin AIII increases the scopolamine-induced reduction in step-through latency by 17% (10 mg/kg), 28% (20 mg/kg), and 43% (40 mg/kg). During the acquisition trial, no differences in latent time are observed. Timosaponin AIII (20, 40 mg/kg, p.o.) potently inhibits this reduction of acetylcholine in scopolamine-treated mouse brain. The inhibitory effect of Timosaponin AIII is comparable to that of tacrine, which is used as a positive control.
相关产品:Natural Product Library Plus | Bioactive Compound Library Plus | Neuronal Signaling Compound Library | Natural Product Library | Anti-Cancer Compound Library | Glycoside Compound Library | Endoplasmic Reticulum Stress Compound Library | Traditional Chinese Medicine Active Compound Library | Anti-Cancer Natural Product Library | Plant-Sourced Natural Product Library | Heterocyclic Compound Library | Membrane Protein-targeted Compound Library | Donepezil Hydrochloride | α-NETA | TMPyP4 tosylate | Galanthamine | Garcinol | Physostigmine salicylate | Scopoletin | Rivastigmine | Protopine | sn-Glycero-3-phosphocholine | (-)-Huperzine A | Protriptyline hydrochloride | Hemicholinium 3 | Imperatorin | Tacrine hydrochloride | Tacrine | Corynoline | Linarin | Pyridostigmine bromide | Buntanetap | Acetylcholinesterase | Epiberberine chloride | Sinapine | Corydaline | Cyanidin-3-O-galactoside chloride | Isoimperatorin | Neostigmine methyl sulfate
热门产品线:重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验。直播者3年收获,分根繁殖者2年收获。趁鲜剥去外皮,用硫磺熏3-4小时,切片晒干或烘干为光知母,也叫知母肉。每公顷可收干货3t。 根茎含知母皂甙(Timosaponin)。味苦,性寒。有滋阴、降火、润燥功能。用于热病烦渴、肺热咳嗽、骨蒸潮热、消褐、肠燥便秘。
技术资料暂无技术资料 索取技术资料

















