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- 英文名:
Neuropeptide Y (13-36), human
- 库存:
货期:电询
- 供应商:
MedChemExpress LLC
- 规格:
500 μg/1 mg/5 mg
| 规格: | 500 μg | 产品价格: | ¥1600.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥2600.0 |
| 规格: | 5 mg | 产品价格: | ¥7800.0 |
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Neuropeptide Y (13-36), amide, human
CAS No. : 122341-40-6
MCE 国际站:Neuropeptide Y (13-36), amide, human
产品活性:Neuropeptide Y (13-36), amide, human 是选择性的神经肽 Y2 受体 (neuropeptide Y2 receptor) 的激动剂。
研究领域:GPCR/G Protein | Neuronal Signaling
作用靶点:Neuropeptide Y Receptor
In Vivo: Neuropeptide Y (13-36) (intraventricular injection; 25-3000 pmol) produces a dose-dependent increase (up to 14%; ED50 value of 0.3 nmol for overall effects and 0.97 nmol for the peak effects) in mean arterial blood pressure in the awake, unrestrained male rat without affecting heart rate. Central administration of porcine Neuropeptide Y (13-36) produces marked vasodepressor and bradycardic actions in the anaesthetized α-chloralose and in the awake unrestrained male rat.
Neuropeptide Y (13-36) (intracerebroventricular injection; 50 ng; alone; injected 30 and 15 min before measurements) injected into naïve mice impairs social novelty preference, but not sociability, and this effect is inhibited by the NPY Y2 receptor antagonist BIIE 0246.
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文献和实验Characterization of Neuropeptide Y (NPY) Receptors
.A., and Weinshank, R.L. 1995. Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y and peptide YY. J. Biol. Chem. 270:26762‐26765.
Human Type 2 Neuropeptide Y Receptor Gene: Isolation and Characterization
two and seven (1 ). One of the sequences identified encoded the partial sequence of a novel protein most closely related to the type 1 neuropeptide Y (NPY) receptor, the only member of the NPY receptor family characterized by molecular cloning at that time
Cloning Neuropeptide Tyrosine cDNA
The nervous system is composed of a diverse population of cells selectively expressing different genes which ultimately determine the type of neurotransmitters and neuropeptides produced and released. Neuropeptide tyrosine (NPY
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