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- 保存条件：
4°C, sealed storage, away from moisture and light
- 英文名：
R18134 nitrate
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
22832-87-7
- 规格：
10 mM * 1 mL/500 mg/1 g/5 g
| 规格： | 10 mM * 1 mL | 产品价格： | ￥500.0 |
|---|---|---|---|
| 规格： | 500 mg | 产品价格： | ￥350.0 |
| 规格： | 1 g | 产品价格： | ￥450.0 |
| 规格： | 5 g | 产品价格： | ￥980.0 |
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Miconazole nitrate
CAS No. : 22832-87-7
MCE 国际站：Miconazole nitrate
产品活性：Miconazole nitrate (R18134 nitrate) 是咪唑类抗真菌剂。Miconazole nitrate 也具有抗菌作用。
研究领域：Anti-infection
作用靶点：Fungal | Bacterial | Antibiotic
In Vitro: Miconazole nitrate (R18134 nitrate) is an imidazole antifungal agent, developed by Janssen Pharmaceutica, commonly applied topically to the skin or to mucous membranes to cure fungal infections. It works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. It can also be used against certain species of Leishmania protozoa which are a type of unicellular parasite that also contain ergosterol in their cell membranes. In addition to its antifungal and antiparasitic actions, it also has some antibacterial properties. Miconazole nitrate (R18134 nitrate) is also used in Ektachrome film developing in the final rinse of the Kodak E-6 process and similar Fuji CR-56 process, replacing formaldehyde. Fuji Hunt also includes miconazole as a final rinse additive in their formulation of the C-41RA rapid access color negative developing process. From Wikipedia.
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文献和实验【摘要】目的建立高效液相色谱法测定咪康唑酊含量的方法。方法采用Shim-packCLC-ODS十八烷基硅烷键合硅胶柱(6.0mm×150mm，5μm),柱温30℃，以乙腈-甲醇-0.5%醋酸铵溶液（42.55∶42.55∶15）为流动相，流速为1.0ml/min，检测波长为230nm。结果在40~800μg/ml浓度范围内，峰面积与浓度呈良好的线性关系，相关系数为0.9997。平均回收率为99.87%，RSD为0.46%。硝酸咪康唑与其他杂质峰的分离度均符合要求。结论本方法简便专属
及毛巾均应用开水烫洗。 2．改变阴道酸碱度用2％～4％碳酸氢钠液冲洗阴道，造成不利于念珠菌生存的条件。 3．杀菌剂以碱性溶液冲洗后，选用下列药物：①克霉唑（clotrimazole）栓剂或片剂，每晚1次，每次1粒或1片，塞入阴道深部，连用7日；②达克宁（硝酸咪康唑miconazole）栓剂，每晚1粒塞入阴道，连用7日；③制霉菌素（nystatin）栓剂或片剂，每晚1次，每次1粒或1片（10万U），连用7～10日；④米可定阴道泡腾片，每晚1片，塞入阴道内，连用5日；⑤1％龙胆紫水溶
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