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- 文献和实验
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
2105956-51-0
- 规格:
1 mg/5 mg/10 mg/25 mg/50 mg
| 规格: | 1 mg | 产品价格: | ¥669.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥1738.0 |
| 规格: | 10 mg | 产品价格: | ¥2463.0 |
| 规格: | 25 mg | 产品价格: | ¥4163.0 |
| 规格: | 50 mg | 产品价格: | ¥5663.0 |
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CDK9-IN-8
CAS No. : 2105956-51-0
MCE 国际站:CDK9-IN-8
产品活性:CDK9-IN-8是高效,选择性的 CDK9 抑制剂,IC50为12 nM。
研究领域:Cell Cycle/DNA Damage
作用靶点:CDK
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文献和实验”。在上述两种物质相互作用的过程中,如果前者占优势,表明乳腺肿瘤患者体内进一步发生病变成为乳腺癌的危险就很低;相反,如果后者占上风,则表明患者体内发生病变成为乳腺癌的危险程度就非常高。这为人类进一步研究有效的药物来治疗女性乳腺癌这一疾病提供了新的可能。 美国犹太医学研究中心的科学家[8]发现了一个可以抑制细胞增殖的蛋白质cdk6, 它对乳腺癌的生长发育起着作用。在乳腺癌细胞中cdk6低水平表达或不表达,而正常细胞相对高水平表达,当两个肿瘤细胞系中cdk6在细胞内表达水平增高时瘤细胞生长明显下降
Two-hybrid analysis of genetic regulatory networks
small sets of proteins as described in Section 2.1 and Protocol 1. In one example of this approach, we used interaction mating to characterize a set of seven Drosophila Cyclin-dependent kinases (Cdk) interactors, or Cdis (Finley and Brent, 1994). Strains
) 191-211 AAGGGGCACAGGCATGCCAAA IMR90E1A Caspase 2 (34) 94-114 AAACAGCTGTTGTTGAGCGAA IMR90E1A hCdc2 (24) 125-147 HeLa Cdc14A (23) 89-109 GCACAGTAAATACCCACTATT HeLa cdk1 (1) NM_001786 125-147 aaggggttcctagtactgcaa Human HeLa CENP-E (1) NM_001813
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