KZR-504,1629052-78-3

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KZR-504

CAS No. : 1629052-78-3

MCE 国际站：KZR-504

产品活性：KZR-504 是高度选择性的免疫原体低分子质量多肽 2 (LMP2) 的抑制剂、其对 LMP2 和 LMP7 的 IC₅₀ 值分别为 51 nM, 4.274 μM。KZR-504 可以用于自身免疫性疾病的研究。

研究领域：Metabolic Enzyme/Protease

作用靶点：Proteasome

In Vivo: Evaluating the inhibition of LMP2, and antitargets LMP7 and β5, in mouse tissues reveals that KZR-504 (compound 12) is both selective and potent in vivo with >50% target inhibition achieved at >1 mg/kg in all tissues tested except brain.

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