- ￥600 - 4200
- MedChemExpress(MCE)
- 美国
- HY-117154
- 2025年12月05日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
1587705-63-2
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥1295.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥600.0 |
| 规格： | 5 mg | 产品价格： | ￥1500.0 |
| 规格： | 10 mg | 产品价格： | ￥2300.0 |
| 规格： | 25 mg | 产品价格： | ￥4200.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
INH154
CAS No. : 1587705-63-2
MCE 国际站：INH154
产品活性：INH154 是 Nek2 和 Hec1 结合的高效抑制剂 (INH)，其在 Hela 和 MB468 细胞中的 IC50 值分别为 200 nM 和 120 nM。
研究领域：Others
作用靶点：Others
In Vitro: INH154 is highly potent in treating breast tumors with co-elevated expression of Hec1 and Nek2. INH154 is the most potent inhibitor of tumor cell growth. The IC50 values of INH154 in HeLa and MDA-MB-468 cancer cells are 0.20 and 0.12 μM, respectively. INH154 also suppresses the growth of leukemia, osteosarcoma, and glioblastoma cells.
In Vivo: Tumor growth rates in mice treated with INH154 are evidently slower than those in control animals in a dose-dependent manner. In agreement with the tumor-growth data, the tumor proliferation index, determined by measuring BrdU staining, is clearly reduced in residual tumors treated with INH154 in comparison with vehicle alone. The expression levels of Nek2 and Hec1 S165 phosphorylation are also substantially reduced in INH154-treated tumors than in vehicle-treated tumors. On the other hand, mice body weights are measured during the 6.5 weeks treatment period and show little difference among treated and control groups. In addition, the toxicity of INHs by treating normal BALB/c ByJNarl mice with high dosage of INH154 (20 mg/kg) shows no significant difference of body weights, blood chemistry, and complete blood count (CBC) analysis among these groups of animals.
相关产品：Bioactive Compound Library Plus | Anti-Cancer Compound Library | Anti-Blood Cancer Compound Library | Targeted Diversity Library | Heterocyclic Compound Library | Digitonin | 5-Ph-IAA | FLAG peptide | Tocofersolan | Monocrotaline | Lactate sodium | TCEP hydrochloride | 3X FLAG peptide | DPPH | Pertussis Toxin | Pronase E (Activity ≥ 7000 U/g) | O-Propargyl-Puromycin | NMDI14 | Phytohemagglutinin | MYLS22 | Hyaluronidase | Biotinyl tyramide | Kifunensine | Human IgG1 kappa, Isotype Control | 4-Azido-L-phenylalanine | 6-Aminonicotinamide | Ammonium tetrathiomolybdate(VI) | OVA Peptide(257-264) TFA | Alkyne-phenol | Lauryl maltose neopentyl glycol | SHIN1 | CHAPS | Cytosporone B
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Seed (2003) A PCR primer bank for quantitative gene expression analysis. Nucleic Acids Research 31(24): e154; pp.1-8. 数据库地址： http://pga.mgh.harvard.edu/primerbank/ 这个数据库的引物设计的规则如下： All the primers in PrimerBank were designed using a program
67.0 B 95 44 46.3 O 154 96 62.3 AB 31 11 35.5 表2 吸烟与Hp的关系 吸烟 n Hp阳性数 % 不 129 68 52.7 吸 248 153 61.7 ～10支/d 52 30 57.7 ～20支/d 155 99 63.9 ＞20支/d 41 24 58.5 表3 饮酒与Hp的关系 饮酒 N Hp阳性数 % 不饮酒 118 67 56.8 偶尔饮酒 125 73 58.4 常饮啤酒 68 40
结核杆菌（mycobecterium tuberculosis）
敏感试验等。 结核杆菌对某些理化因子的抵抗力较强。在干痰中存活6～8个月，若粘附于尘埃上，保持传染性8～10天。在3%hci或naoh溶液中能耐受30分钟，因而常以酸硷中和处理严重污染的检材，杀死杂菌和消化粘稠物质，提高检出率。但对湿热、紫外线、酒精的抵抗力弱。在液体中加热62～63℃15分钟，直射日光下2～3小时，75%酒精内数分钟即死亡。 结核杆菌对链霉素、利福平、异烟肼等抗结核药物较易产生耐药性。耐药菌菌株常伴随活力和毒力减弱，如异烟肼耐药菌株对豚鼠的毒力
技术资料暂无技术资料 索取技术资料
