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- 2025年12月05日
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- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
KB2115
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
355129-15-6
- 规格：
10 mM * 1 mL/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥400.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥373.0 |
| 规格： | 10 mg | 产品价格： | ￥591.0 |
| 规格： | 25 mg | 产品价格： | ￥1185.0 |
| 规格： | 50 mg | 产品价格： | ￥1863.0 |
| 规格： | 100 mg | 产品价格： | ￥2988.0 |
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Eprotirome
CAS No. : 355129-15-6
MCE 国际站：Eprotirome
产品活性：Eprotirome (KB2115) 是肝脏选择性甲状腺激素受体 (thyroid hormone receptor, TR) 激动剂。KB2115 对 TRβ 的亲和力略高于 TRα。Eprotirome 降低了低密度脂蛋白 (LDL) 胆固醇的浓度，可用于血脂异常和肥胖症的研究。
研究领域：Vitamin D Related/Nuclear Receptor
作用靶点：Thyroid Hormone Receptor
In Vivo: Eprotirome is a liver-selective thyroid hormone receptor agonist. Histological analysis of livers from mice treated with Eprotirome reveals that Eprotirome elicits a near complete elimination of lipid filled vacuoles that are characteristic of the livers from untreated control mice. Eprotirome treated mice also exhibit increased fasting glucose, but Eprotirome does not increase fasting insulin levels. Glucose levels of mice treated with Eprotirome continues to increase over time, leading to pronounced hyperglycemia by the end of the study. Temperature of mice treated with Eprotirome is decreased relative to untreated control mice.
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