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文献和实验Evaluating Modulators of “Regulator of G‐protein Signaling” (RGS) Proteins
?protein Signaling? (RGS) proteins constitute a class of intracellular signaling regulators that accelerate GTP hydrolysis by heterotrimeric G? subunits. In recent years, RGS proteins have emerged as potential drug targets for modulation by small molecules
Protein Microarrays for Identification of Novel Extracellular Protein‐Protein Interactions
) PBS (see recipe ) Bait protein: can be any extracellular protein of interest to the investigator, e.g., an orphan receptor that functions in cellular communication
Detecting Low‐Affinity Extracellular Protein Interactions Using Protein Microarrays
., and Wright, G.J. 2010. Construction of a large extracellular protein interaction network and its resolution by spatiotemporal expression profiling. Mol. Cell Proteomics 9:2654‐2665.
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