Invitrogen Transferrin Recepto

Invitrogen

Transferrin Receptor Monoclonal Antibody (H68.4)

货号 13-6800

CNY 4,443.00




 

产品详细信息

H68.4 is specific to residues 3-28 of the human transferrin receptor (TfR) tail.

靶标信息

CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions), CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface, where it is released upon exposure to normal pH. CD71 is also involved in uptake of non-transferrin bound iron.

仅用于科研。不用于诊断过程。未经明确授权不得转售。