- ￥1350 - 3000
- Proteintech
- 18984-1-AP
- 2025年10月13日
- IHC, IF-P, ELISA
- Rabbit
- human, mouse, rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
None
- 亚型：
IgG
- 保存条件：
Store at -20°C. Stable for one year after shipment.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
human, mouse, rat
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Rabbit
- 应用范围：
IHC, IF-P, ELISA
- 靶点：
nNOS
- 抗体英文名：
nNOS Polyclonal antibody
- 抗体名：
nNOS Polyclonal antibody
- 规格：
50ul/100ul/150ul
| 规格： | 50ul | 产品价格： | ￥1350.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2200.0 |
| 规格： | 150ul | 产品价格： | ￥3000.0 |
经过测试的应用
| Positive IHC detected in | mouse heart tissue, mouse kidney tissue, rat testis tissue, mouse brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF-P detected in | mouse brain tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
18984-1-AP targets nNOS in IHC, IF-P, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | IHC, IF-P, ELISA |
| 文献引用应用 | IHC |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human, mouse, rat, pig, canine |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | nitric oxide synthase 1 (neuronal) |
| 别名 | NOS1, N-NOS, NC-NOS, NC NOS, N NOS |
| 计算分子量 | 161 kDa |
| GenBank蛋白编号 | NM_000620 |
| 基因名称 | nNOS |
| Gene ID (NCBI) | 4842 |
| RRID | AB_10598169 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P29475 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
nNOS belongs to the NOS family. nNOS produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. NO is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. NO is synthesized from L-arginine by nitric oxide synthases. nNOS is a nitric oxide synthase which is highly expressed in skeletal muscle. Genetic variations in nNOS gene are associated with susceptibility to infantile hypertrophic pyloric stenosis type 1 (IHPS1). The antibody can recognize isoform 1,2,4 of nNOS.
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文献和实验| Species | Application | Title |
|---|---|---|
| human | IHC | Mod Pathol Neuronal distribution in colorectal cancer: associations with clinicopathological parameters and survivalAuthors - Maartje Massen |
| mouse | ACS Chem Neurosci Antidepressant-like Effect of Merazin Hydrate Depends on NO/ERK by Suppressing Its Downstream NF-κB or Nonactivating CREB/BDNF in Mouse Hippocampus.Authors - Lei Wu | |
| canine | IHC | Exp Eye Res Altered transsulfuration pathway enzymes and redox homeostasis in inherited retinal degenerative diseases.Authors - Alireza Badiei |
| rat | Acta Pharmacol Sin Neuroprotective effects of scutellarin on rat neuronal damage induced by cerebral ischemia/reperfusion.Authors - Hu Xia-Min XM | |
| mouse | Biochim Biophys Acta Mol Cell Res NMDA receptor activation induces damage of alveolar type II cells and lung fibrogenesis through ferroptosisAuthors - Hai-Peng Cheng | |
| pig | IHC | Eur J Pharmacol Suppressive effect of nitric oxide synthase (NOS) inhibitor L-NMMA acetate on choroidal fibrosis in experimental myopic guinea pigs through the nitric oxide signaling pathwayAuthors - Tuling Li |
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