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SLC32A1/VGAT 多克隆抗体 14471-1-AP

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  • ¥1350 - 3000
  • Proteintech已认证
  • 14471-1-AP
  • 2025年10月13日
  • WB, IHC, IF-P, IF-Fro, IP, ELISA
  • Rabbit
  • human, mouse, rat
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    • 详细信息
    • 询价记录
    • 文献和实验
    • 技术资料
    • 免疫原

      Recombinant human SLC32A1 protein

    • 亚型

      IgG

    • 保存条件

      Store at -20°C. Stable for one year after shipment.

    • 克隆性

      Polyclonal

    • 标记物

      Unconjugated

    • 适应物种

      human, mouse, rat

    • 保质期

      详见产品包装

    • 库存

      充足

    • 宿主

      Rabbit

    • 应用范围

      WB, IHC, IF-P, IF-Fro, IP, ELISA

    • 靶点

      SLC32A1/VGAT

    • 抗体英文名

      SLC32A1/VGAT Polyclonal antibody

    • 抗体名

      SLC32A1/VGAT Polyclonal antibody

    • 规格

      50ul/100ul/150ul

    规格:50ul产品价格:¥1350.0
    规格:100ul产品价格:¥2200.0
    规格:150ul产品价格:¥3000.0

    经过测试的应用

    Positive WB detected inunboiled mouse brain tissue
    Positive IP detected inmouse brain tissue
    Positive IHC detected inrat brain tissue, mouse brain tissue
    Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
    Positive IF-P detected inrat brain tissue, mouse brain tissue
    Positive IF-Fro detected inrat brain tissue
    Planning an IF experiment? We recommend our CoraLite® Plus 488 conjugated versions of this antibody.

    推荐稀释比

    应用推荐稀释比
    Western Blot (WB)WB : 1:2000-1:10000
    Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
    Immunohistochemistry (IHC)IHC : 1:50-1:500
    Immunofluorescence (IF)-PIF-P : 1:50-1:500
    Immunofluorescence (IF)-FROIF-FRO : 1:50-1:500
    It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    14471-1-AP targets SLC32A1/VGAT in WB, IHC, IF-P, IF-Fro, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

    经测试应用 WB, IHC, IF-P, IF-Fro, IP, ELISA
    文献引用应用WB, IHC, IF
    经测试反应性 human, mouse, rat
    文献引用反应性human, mouse, caenorhabditis elegans
    免疫原

    CatNo: Ag5843

    Product name: Recombinant human SLC32A1 protein

    Source: e coli.-derived, PGEX-4T

    Tag: GST

    Domain: 1-124 aa of BC053582

    Sequence: MATLLRSKLSNVATSVSNKSQAKMSGMFARMGFQAATDEEAVGFAHCDDLDFEHRQGLQMDILKAEGEPCGDEGAEAPVEGDIHYQRGSGAPLPPSGSKDQVGGGGEFGGHDKPKITAWEAGWN

    宿主/亚型 Rabbit / IgG
    抗体类别 Polyclonal
    产品类型 Antibody
    全称 solute carrier family 32 (GABA vesicular transporter), member 1
    别名 SLC32A1, VGAT, GABA and glycine transporter, hVIAAT, Vesicular GABA transporter
    计算分子量 57 kDa
    观测分子量 57 kDa
    GenBank蛋白编号BC053582
    基因名称 VGAT
    Gene ID (NCBI) 140679
    RRIDAB_10644324
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Antigen affinity purification
    UNIPROT IDQ9H598
    储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
    储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

    背景介绍

    SLC32A1, also known as VGAT (vesicular GABA transporter), functions in the uptake of GABA and glycine into synaptic vesicles. GABA (gamma-aminobutyric acid), is the major inhibitory neurotransmitter in the CNS. VGAT transports GABA and glycine into acidic vesicles and localizes to the synaptic vesicle in glycinergic and GABAergic neurons. And VGAT antibodies are useful markers for presynaptic GABAergic and glycinergic neurons.

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    • 作者
    • 内容
    • 询问日期
    图标文献和实验
    该产品被引用文献
    SpeciesApplicationTitle
    mouseWB

    Acta Neuropathol Commun

    Mutation-induced loss of APP function causes GABAergic depletion in recessive familial Alzheimer's disease: analysis of Osaka mutation-knockin mice.

    Authors - Tomohiro Umeda
    humanWB

    Biochem J

    Role of N-glycosylation in renal betaine transport.

    Authors - Eva S Schweikhard
    mouseWB

    Biol Trace Elem Res

    Effect of Voluntary Wheel Running on Anxiety- and Depression-Like Behaviors in Fluoride-Exposed Mice

    Authors - Mengjie Qi
    Caenorhabditis elegansIHC,IF

    PLoS One

    Mutant TDP-43 and FUS cause age-dependent paralysis and neurodegeneration in C. elegans.

    Authors - Vaccaro Alexandra A
    humanIF

    Curr Issues Mol Biol

    miR-92a-2-5p Regulates the Proliferation and Differentiation of ASD-Derived Neural Progenitor Cells.

    Authors - Wenting Zhuang
    mouseWB

    Biol Trace Elem Res

    Exercise Ameliorates Fluoride-induced Anxiety- and Depression-like Behavior in Mice: Role of GABA.

    Authors - Qiqi Cao
    相关实验
    • 有适合免疫沉淀IP的GST抗体吗?

      因此,综合来说,EarthOx的GST标签抗体 (货号#E022040)是一款同时具有高特异性、高灵敏度、多应用类型以及性价比的GST标签抗体。同时,我们也提供其他品牌的GST标签抗体,如Proteintech的GST多克隆抗体 ――GST PolyClonal Antibody(货号#10000-0-AP)以及Abcam、Santa等多种GST标签抗体产品。更多GST标签抗体以及其他如His、HA、Myc、GFP、Flag等其他标签抗体,请电话垂询。美国EarthOx品牌是一家提供高性价比免疫学和细胞

    • Microarray Approaches for Analysis of Cell Cycle Regulatory Genes

      Cell cycle phase Mammalian Yeast G0/G1 AP-1 family (FOS, JUN)

    • 线粒体和凋亡

      同时,Apaf―1可以激活原形的caspase―9,形成细胞色素C/Apaf―1/caspase―9复合体,即凋亡复合体(apoptosome)。该复合体水解并激活下游的caspase通路如caspase―3等。     凋亡复合体的形成是凋亡信号启动的关键步骤。目前发现激活的癌基因可以辅助凋亡复合体的形成,比如腺病毒EIA可以上调Apaf―1和caspase―9,E2F1可以上调Apaf―1的表达。Apaf―1的释放可促进凋亡复合体的形成,对凋亡的启动起促进作用。目前的研究认为,细胞

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    SLC32A1/VGAT 多克隆抗体 14471-1-AP
    ¥1350 - 3000