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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant human Uteroglobin protein
- 亚型:
IgG
- 保存条件:
Store at -20°C. Stable for one year after shipment.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
human, mouse, rat
- 保质期:
详见产品包装
- 库存:
充足
- 宿主:
Rabbit
- 应用范围:
IHC, IF-P, FC (Intra), ELISA
- 靶点:
Uteroglobin/CC10
- 抗体英文名:
Uteroglobin/CC10 Polyclonal antibody
- 抗体名:
Uteroglobin/CC10 Polyclonal antibody
- 规格:
50ul/100ul/150ul
| 规格: | 50ul | 产品价格: | ¥1350.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥2200.0 |
| 规格: | 150ul | 产品价格: | ¥3000.0 |
经过测试的应用
| Positive IHC detected in | mouse lung tissue, human lung cancer tissue, rat lung tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF-P detected in | mouse lung tissue |
| Positive FC (Intra) detected in | A549 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:2000-1:8000 |
| Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
10490-1-AP targets Uteroglobin/CC10 in WB, IHC, IF-P, FC (Intra), IP, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | IHC, IF-P, FC (Intra), ELISA |
| 文献引用应用 | WB, IHC, IF, IP |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human, mouse, bovine |
| 免疫原 |
CatNo: Ag0758 Product name: Recombinant human Uteroglobin protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-91 aa of BC004481 Sequence: MKLAVTLTLVTLALCCSSASAEICPSFQRVIETLLMDTPSSYEAAMELFSPDQDMREAGAQLKKLVDTLPQKPRESIIKLMEKIAQSSLCN |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | secretoglobin, family 1A, member 1 (uteroglobin) |
| 别名 | SCGB1A1, Uteroglobin, CC10, CC16, CCPBP |
| 计算分子量 | 10 kDa |
| GenBank蛋白编号 | BC004481 |
| 基因名称 | Uteroglobin |
| Gene ID (NCBI) | 7356 |
| RRID | AB_2183285 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P11684 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Uteroglobin, also known as CC10, is a member of the secretoglobin family of small secreted proteins. It is produced by the nonciliated, nonmucous, secretory epithelial clara cells of the pulmonary airways, was first identified in lung lavage by Singh and colleagues. It has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma.
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文献和实验| Species | Application | Title |
|---|---|---|
| human | IHC | Nature SARS-CoV-2 Omicron variant replication in human bronchus and lung ex vivo.Authors - Kenrie P Y Hui |
| human | IF | Nat Genet Spatially resolved transcriptomic analysis of the adult human prostateAuthors - Junyi Hu |
| human | IHC | Lancet Respir Med Tropism, replication competence, and innate immune responses of the coronavirus SARS-CoV-2 in human respiratory tract and conjunctiva: an analysis in ex-vivo and in-vitro cultures.Authors - Kenrie P Y Hui |
| human | IHC | Theranostics A SCID mouse-human lung xenograft model of SARS-CoV-2 infection.Authors - Wenkun Fu |
| human | IF | PLoS Pathog Lung adenocarcinoma originates from retrovirus infection of proliferating type 2 pneumocytes during pulmonary post-natal development or tissue repair.Authors - Murgia Claudio C |
| human,mouse | WB,IF | Am J Respir Cell Mol Biol DACH1 Attenuates Airway Inflammation in COPD by Activating NRF2 SignalingAuthors - Qian Huang |
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