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Anti-CHRNA7 Polyclonal Antibod

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  • ¥960 - 1600
  • Solarbio已认证
  • 北京
  • K002857P
  • 2025年10月11日
  • Rabbit
  • Human Mouse Rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Recombinant protein of human CHRNA7

    • 亚型

      IgG

    • 形态

      液体

    • 保存条件

      Store at -20°C. Avoid freeze / thaw cycles.

    • 克隆性

      单克隆

    • 适应物种

      Human Mouse Rat

    • 目录编号

      K002857P

    • 库存

      999

    • 供应商

      北京索莱宝科技有限公司

    • 宿主

      Rabbit

    • 靶点

      CHRNA7

    • 抗体英文名

      Anti-CHRNA7 Polyclonal Antibody

    • 抗体名

      CHRNA7-2;NACHRA7

    • 规格

      50ul/100ul

    规格:50ul产品价格:¥960.0
    规格:100ul产品价格:¥1600.0
    产品简介
    单位
    英文名称 Anti-CHRNA7 Polyclonal Antibody
    别名 CHRNA7-2;NACHRA7
    宿主 Rabbit
    稀释比例 WB 1:500-2000. IHC 1:50-200.
    Gene ID 1139
    保存 Store at -20°C. Avoid freeze / thaw cycles.
    Swiss Prot P36544
    蛋白分子量 56kDa
    储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    亚细胞定位 Cell junction Cell membrane Multi-pass membrane protein postsynaptic cell membrane synapse
    免疫原 Recombinant protein of human CHRNA7
    亚型 IgG
    性状 液体
    纯化方法 Affinity purification
    背景资料 The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. The protein encoded by this gene forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia. An evolutionarily recent partial duplication event in this region results in a hybrid containing sequence from this gene and a novel FAM7A gene. Alternative splicing results in multiple transcript variants.
    Public Immunogen Range Recombinant protein of human CHRNA7
    克隆类型 Polyclonal Antibody
    交叉反应 Human Rat Mouse
    应用 WB IHC
    规格 50ul 100ul

    备注:
    以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
    These protocols are for reference only. Solarbio does not independently validate these methods.
    温馨提示:
    使用前请离心。如有问题请及时联系我们。
    Quick spin before use. If you have any questions, please contact us.
    实验图
    产品细节图片1
    Western blot analysis with CHRNA7 antibody diluted at 1:1000
    产品细节图片2
    Immunohistochemistry of paraffin-embedded skin cancer(hu) using CHRNA7 antibody at dilution of 1:100 (x100 lens).
    Anti-CHRNA7 Polyclonal Antibody
    宿主 Rabbit
    别名 CHRNA7-2;NACHRA7
    稀释比例 WB 1:500-2000. IHC 1:50-200.
    蛋白分子量 56kDa
    Gene ID 1139
    保存 Store at -20°C. Avoid freeze / thaw cycles.
    储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    纯化方法 Affinity purification
    亚型 IgG
    免疫原 Recombinant protein of human CHRNA7
    性状 液体
    Public Immunogen Range Recombinant protein of human CHRNA7
    亚细胞定位 Cell junction Cell membrane Multi-pass membrane protein postsynaptic cell membrane synapse
    Swiss Prot P36544
    克隆类型 Polyclonal Antibody
    背景资料 The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. The protein encoded by this gene forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia. An evolutionarily recent partial duplication event in this region results in a hybrid containing sequence from this gene and a novel FAM7A gene. Alternative splicing results in multiple transcript variants.
    应用    WB IHC
    交叉反应    Human Mouse Rat
    规格    50ul    100ul

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    图标文献和实验
    相关实验
    • Polyclonal Antibody Production

      , if desired this is best accomplished by Protein A Affinity Chromatography.   上一篇:make an Antibody against a Peptides   下一篇:Immunization Protocol for Monoclonal Antibody Production

    • Polyclonal Antibody Production

        Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation.     Rabbit Immunization Initial Preparation Your antigen

    • Human Anti-antibody Response

      a simple ELISA method to detect human anti-antibody response.

    图标技术资料

    暂无技术资料 索取技术资料

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