- ￥960 - 1600
- Solarbio
- 北京
- K001450M
- 2025年09月30日
- Mouse
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Purified recombinant full length of human IgM heavy chain protein expressed in E.coli.
- 亚型：
IgG2a
- 形态：
液体
- 保存条件：
Store at -20°C. Avoid freeze / thaw cycles.
- 克隆性：
单克隆
- 适应物种：
Human
- 目录编号：
K001450M
- 库存：
999
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Mouse
- 靶点：
Human IgM
- 抗体英文名：
Anti-Human IgM Monoclonal Antibody
- 抗体名：
Human IgM
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
产品简介
备注： 以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。 These protocols are for reference only. Solarbio does not independently validate these methods. 温馨提示： 使用前请离心。如有问题请及时联系我们。 Quick spin before use. If you have any questions, please contact us. |
Anti-Human IgM Monoclonal Antibody | ||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 宿主 | Mouse | ||||||||||||||||||||||||||||||||||||||||||||
| 别名 | Human IgM | ||||||||||||||||||||||||||||||||||||||||||||
| 稀释比例 | WB 1:1000. | ||||||||||||||||||||||||||||||||||||||||||||
| 蛋白分子量 | 75kDa | ||||||||||||||||||||||||||||||||||||||||||||
| Gene ID | 3507 | ||||||||||||||||||||||||||||||||||||||||||||
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. | ||||||||||||||||||||||||||||||||||||||||||||
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | ||||||||||||||||||||||||||||||||||||||||||||
| 纯化方法 | Affinity purification | ||||||||||||||||||||||||||||||||||||||||||||
| 亚型 | IgG2a | ||||||||||||||||||||||||||||||||||||||||||||
| 免疫原 | Purified recombinant full length of human IgM heavy chain protein expressed in E.coli. | ||||||||||||||||||||||||||||||||||||||||||||
| 性状 | 液体 | ||||||||||||||||||||||||||||||||||||||||||||
| Public Immunogen Range | Purified recombinant full length of human IgM heavy chain protein expressed in E.coli. | ||||||||||||||||||||||||||||||||||||||||||||
| 亚细胞定位 | Cell membrane Secreted | ||||||||||||||||||||||||||||||||||||||||||||
| Swiss Prot | P01871 | ||||||||||||||||||||||||||||||||||||||||||||
| 克隆号 | 3E12-H4-G4 | ||||||||||||||||||||||||||||||||||||||||||||
| 克隆类型 | Monoclonal Antibody | ||||||||||||||||||||||||||||||||||||||||||||
| 背景资料 | Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains and 2 identical light chains (see MIM 147200) joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. Each Ig heavy chain has an N-terminal variable (V) region containing the antigen-binding site and a C-terminal constant (C) region, encoded by an individual C region gene, that determines the isotype of the antibody and provides effector or signaling functions. The heavy chain V region is encoded by 1 each of 3 types of genes: V genes (see MIM 147070), joining (J) genes (see MIM 147010), and diversity (D) genes (see MIM 146910). The C region genes are clustered downstream of the V region genes within the heavy chain locus on chromosome 14. The IGHM gene encodes the C region of the mu heavy chain, which defines the IgM isotype. Naive B cells express the transmembrane forms of IgM and IgD (see IGHD; MIM 1471770) on their surface. During an antibody response, activated B cells can switch to the expression of individual downstream heavy chain C region genes by a process of somatic recombination known as isotype switching. In addition, secreted Ig forms that act as antibodies can be produced by alternative RNA processing of the heavy chain C region sequences. Although the membrane forms of all Ig isotypes are monomeric, secreted IgM forms pentamers, and occasionally hexamers, in plasma | ||||||||||||||||||||||||||||||||||||||||||||
| 应用 | ELISA | ||||||||||||||||||||||||||||||||||||||||||||
| 交叉反应 | Human | ||||||||||||||||||||||||||||||||||||||||||||
| 规格 | 50ul 100ul |
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文献和实验相关实验
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指仅对一种抗原决定基的纯粹的抗体。这类抗体不可能通过将抗原 胞的 Hybridoma，在试管内制成了纯粹的单克隆抗体。用某种抗原使动物产生免疫感应，对应于抗原之不同部分可制成各种不同的抗体复合体。然而，因为一个产生抗体的细胞，只能产生一种抗体，所以骨髓肿瘤细胞与产生抗体细胞间的细胞杂种，可形成边产生抗体边增殖的 hybridoma，将每个杂种细胞进行克隆（无性繁殖系）培养，则一个克隆的细胞群只由单种类产生同一抗体的细胞所组成，这样得到的就是单克隆抗体。此抗体在测定
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Anti-Human IgM Monoclonal Antibody
￥960 - 1600
