- ￥960 - 1600
- Solarbio
- 北京
- K000359P
- 2025年07月15日
- Rabbit
- Human Mouse
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- 详细信息
- 技术资料
- 免疫原：
Recombinant protein of human MSR1
- 亚型：
IgG
- 形态：
液体
- 保存条件：
Store at -20°C. Avoid freeze / thaw cycles.
- 克隆性：
单克隆
- 适应物种：
Human Mouse
- 目录编号：
K000359P
- 库存：
999
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 靶点：
MSR1
- 抗体英文名：
Anti-MSR1 Polyclonal Antibody
- 抗体名：
CD204;SCARA1;SR-A;SR-AI;SR-AII;SR-AIII;SRA;phSR1;phSR2
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 英文名称 | Anti-MSR1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD204;SCARA1;SR-A;SR-AI;SR-AII;SR-AIII;SRA;phSR1;phSR2;macrophage scavenger receptor 1 |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:10-100. |
| 蛋白分子量 | 50kDa |
| Gene ID | 4481 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human MSR1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human MSR1 |
| 亚细胞定位 | Membrane Single-pass type II membrane protein |
| Swiss Prot | P21757 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. |
| 应用 | WB IHC IF |
| 交叉反应 | Human Mouse |
| 规格 | 50ul 100ul |
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Anti-MSR1 Polyclonal Antibody
￥960 - 1600
