- ￥960 - 1600
- Solarbio
- 北京
- K000082M
- 2025年07月13日
- WB
- Mouse
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Purified recombinant human Cytochrome P450 17A1 protein fragments expressed in E.coli.
- 亚型：
IgG2b
- 形态：
液体
- 保存条件：
Store at -20°C. Avoid freeze / thaw cycles.
- 克隆性：
单克隆
- 标记物：
详询
- 适应物种：
Human
- 保质期：
详询
- 抗原来源：
详询
- 目录编号：
K000082M
- 级别：
详询
- 库存：
999
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Mouse
- 应用范围：
WB
- 浓度：
详询
- 靶点：
Cytochrome P450 17A1
- 抗体英文名：
Anti-Cytochrome P450 17A1 Monoclonal Antibody
- 抗体名：
CPT7;CYP17;P450C17;S17AH
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
产品简介
|
英文名称
|
Anti-CYP17A1 Monoclonal Antibody
|
|
中文名称
|
细胞色素P450 17A1抗体
|
|
靶标
|
CYP17A1
|
|
别名
|
CPT7, CYP17, CYP17A1, Cytochrome P450 17A1, CYPXVII, Cytochrome P450 family 17, Cytochrome P450 family 17 subfamily A polypeptide 1, Cytochrome p450 XVIIA1, Cytochrome p450, subfamily XVII (steroid 17 alpha hydroxylase) adrenal hyperplasia , P450 C17, P450c17, S17AH, Steroid 17 alpha hydroxylase/17,20 lyase, Steroid 17 alpha monooxygenase, CP17A_HUMAN
|
|
背景资料
|
This gene encodes a member of the cytochrome P450 superfamily of enzymes.The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol,steroids and other lipids.This protein localizes to the endoplasmic reticulum.It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins,mineralocorticoids,glucocorticoids,androgens,and estrogens.Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency,17-alpha-hydroxylase/17,20-lyase deficiency,pseudohermaphroditism,and adrenal hyperplasia.[provided by RefSeq,Jul 2008]
|
|
Swiss Prot
|
P05093
|
|
Gene ID
|
1586
|
|
亚细胞定位
|
Membrane
|
|
宿主
|
Mouse
|
|
克隆类型
|
Monoclonal Antibody
|
|
亚型
|
IgG2b
|
|
克隆号
|
6E1-H9-F6
|
|
交叉反应
|
Human
|
|
蛋白分子量
|
57kDa
|
|
应用
|
WB
|
|
稀释比例
|
WB 1:500-1000.
|
|
免疫原
|
Recombinant protein of human CYP17A1
|
|
纯化方法
|
Affinity purification
|
|
储存液
|
Buffer: PBS with 0.02% sodium azide, 0.5% BSA, 50% glycerol, pH7.3.
|
|
保存
|
Store at -20℃. Avoid freeze / thaw cycles.
|
|
规格
|
100ul ; 50ul
|
|
单位
|
支
|
These protocols are for reference only. Solarbio does not independently validate these methods.
Quick spin before use. If you have any questions, please contact us.
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文献和实验Monoclonal Antibodies to Cytochromes P450
specifically recognizes a single antigenic determinant or “epltope” on the protein antigen, which, in our studies, is a specific individual cytochrome P450 (P450). This specificity of the MAb continues for the lifetime of the hybridoma cell, which can be frozen
In Vitro Identification of Cytochrome P450 Enzymes Responsible for Drug Metabolism
Metabolism catalyzed by the cytochrome P450 enzymes (CYPs) represents the most important pathway for drug metabolism and elimination in humans. Identification of the CYPs responsible for metabolism of existing and novel drugs is critical
Protocol for anti-HA antibody Western Blotting
film for ~2 mins. Notes on the primary antibody: Source : Covance/Babco Description: Crude ascites fluid monoclonal anti-HA antibody (CATLN#135032002, 11mms-101R, 0.5 ml) Handling: Aliquoted into 10ul portions in -20℃ Internal notes: labelled anti
