- ￥960 - 1600
- Solarbio
- 北京
- K000037M
- 2025年07月07日
- WB
- Mouse
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Purified recombinant human FAS (C-terminus) protein fragments expressed in E.coli.
- 亚型：
IgG1
- 形态：
液体
- 保存条件：
Store at -20°C. Avoid freeze / thaw cycles.
- 克隆性：
单克隆
- 标记物：
详询
- 适应物种：
Human
- 保质期：
详询
- 抗原来源：
详询
- 目录编号：
K000037M
- 级别：
详询
- 库存：
999
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Mouse
- 应用范围：
WB
- 浓度：
详询
- 靶点：
FAS(C-term)
- 抗体英文名：
Anti-FAS(C-term) Monoclonal Antibody
- 抗体名：
ALPS1A;APO-1;APT1;CD95;FAS1;FASTM;TNFRSF6
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 英文名称 | Anti-FAS(C-term) Monoclonal Antibody |
|---|---|
| 宿主 | Mouse |
| 别名 | ALPS1A;APO-1;APT1;CD95;FAS1;FASTM;TNFRSF6 |
| 稀释比例 | WB 1:1000. |
| 蛋白分子量 | 38kDa |
| Gene ID | 355 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG1 |
| 免疫原 | Purified recombinant human FAS (C-terminus) protein fragments expressed in E.coli. |
| 性状 | 液体 |
| Public Immunogen Range | Purified recombinant human FAS (C-terminus) protein fragments expressed in E.coli. |
| 亚细胞定位 | Cell membrane Secreted Single-pass type I membrane protein |
| Swiss Prot | P25445 |
| 克隆号 | 4C3-G7-B7-H5 |
| 克隆类型 | Monoclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. At least eight alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. |
| 应用 | WB |
| 交叉反应 | Human |
| 规格 | 50ul 100ul |
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文献和实验指仅对一种抗原决定基的纯粹的抗体。这类抗体不可能通过将抗原 胞的 Hybridoma，在试管内制成了纯粹的单克隆抗体。用某种抗原使动物产生免疫感应，对应于抗原之不同部分可制成各种不同的抗体复合体。然而，因为一个产生抗体的细胞，只能产生一种抗体，所以骨髓肿瘤细胞与产生抗体细胞间的细胞杂种，可形成边产生抗体边增殖的 hybridoma，将每个杂种细胞进行克隆（无性繁殖系）培养，则一个克隆的细胞群只由单种类产生同一抗体的细胞所组成，这样得到的就是单克隆抗体。此抗体在测定
Monoclonal Antibody Production
Order 6 six week old Balb/C mice and let the ARC know they are coming.Have your antigen ready for when they arrive.Once they get there earmark the mice and perform a pre-bleed on them to be used as an ELISA control for monitoring the titer
a simple ELISA method to detect human anti-antibody response.
