Rat gp130 / IL6ST / CD130 Prot

分子别名（Synonym）:IL6ST 种属（Species）：Rat 表达系统（Expressed Host）：HEK293 Cells 制剂（Buffer）：Lyophilized from sterile PBS, pH 7.4 分子量（Molecule Mass）：The recombinant rat IL6ST/Fc is a disulfide-linked homodimer. The reduced monomer comprises 839 amino acids and predicts a molecular mass of 94.3 kDa. The apparent molecular mass of the rat IL6ST/Fc monomer is approximately 130 kDa in SDS-PAGE under reducing conditions due to glycosylation. 内毒素（Endotoxin）：＜1.0 EU per μg by the LAL method. 生物活性(Activity)：Measured by its ability to inhibit the IL6 Rα enhancement of IL6 activity on M1 mouse myeloid leukemia cells (Saito, T. et al. 1991, J. Immunol. 147:168.). The ED50 for this effect is typically 0.015-0.075 μg/ml in the presence of 50 ng/ml recombinant human IL6sR and 100 ng/ml recombinant human IL6. 表达区间（Protein Construction）：A DNA sequence encoding the rat IL6ST (NP_001008725.2) extracellular domain (Met 4-Glu 618) was fused with the C-terminal polyhistidine-tagged Fc region of mouse IgG1 at the C-terminus. 存储条件（Storage）： For long term storage, the product should be stored at lyophilized state at -20℃ or lower.Please avoid repeated freeze-thaw cycles. No activity loss is observed after storage at:4-8℃ for 12 months in lyophilized state;-70℃ for 3 months under sterile conditions after reconstitution. 运输条件： In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.