Mouse Anti Human Fascin Actin-

Strongylocentrotus Purpuratus, actin-bundling protein, FAN1, HSN, SNL.

Mouse Anti Human Monoclonal.

FSCN1 is an actin-bundling protein that is responsible for rigidity to filopodial bundles to efficiently push the membrane forward during cytoskeleton remodeling and cell migration. FSCN1 takes part in the gathering of actin filament bundles present in microspikes, membrane ruffles, and stress fibers. FSCN1 is absent from most normal epithelia though is upregulated in multiple forms of human carcinoma, where its expression associates clinically with a poor prognosis. FSCN1 expression is abundantly found in neurons, glial cells, and endothelial cells.

PAT13D2AT.

Sterile filtered colorless solution.

Anti-human FSCN1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human FSCN1 protein 1-493 amino acids purified from E. coli.

Mouse IgG_2b heavy chain and k light chain.

FSCN1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.

1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.

12 months at -20°C. 1 month at 4°C.

FSCN1 antibody has been tested by ELISA, Western blot analysis, ICC/IF and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

SDS

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.